SSRIs

Reduced seizure threshold.

Bipolar people

patients with a high bleeding risk (>80 or previous GI risk) SSRI's increase bleeding risk.

Serotonin toxicity - if an SSRI is taken within 14 days of finishing a MAOI. Or within 2 days of stopping metoclopramide).

Children - only use fluvoxamine or sertraline

CI in treatment with pimozide.

Nausea, agitation, insomnia, drowsiness, tremor,

extrapyridimal reactions, sedation, confusion, hypotension, hyponaturaemia (as part of SIADH)

20mg once daily, increasing after 2-4 weeks to a max of 60mg daily for OCD or eating disorders

40mg max in elderly

For depression maintaince - not usually more than 20mg daily.

10mg once daily in the morning, icrease upto 20mg.

major depression - 20mg once daily, increasing upto 60mg daily if needed.

OCD - 20mg once daily

Panic Disorder - 10mg once daily

Premenstural disorder - 20mg daily (continious) or 20mg daily starting 14 days before menstuaraion until first full day of menstural cycle (cyclic)

20mg daily

GAD etc = 10mg once daily, increasing to 20mg daily after a week if required.

20mg once daily

Depression - 50mg daily, increasing upto 200mg max.

Obsessive compulsive disorder - 25mg daily

Panic disorder - 25mg daily

Take in the morning

Do not drive or operate machinery until you know how this medication affects you.

Do not stop taking this medication unless told to by the doctor

Tell doctors, pharmacists and any other medical team that you are taking this med since it can interact with many other meds

5 mg at night, increasing gradually as indicated to 30–45 mg at night. Maximum 60 mg.