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patients with renal insufficiency should be cautious when taking medications that contain what?
magnesium
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magnesium has what kind of effect on the body?
laxative effect
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these are alkaline chemical agents that reduce corrosiveness of gastric acid and decrease pepsin activity
antacids
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these are used for relief of symptoms of hyperacidity and PUD, the primary goal being the relief of pain by neutralizing acids
Antacids
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this type of antacid is rapidly absorbed in the stomach and sm. intestine and are capable of causing pH changes in the blood
systemic antacid
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long term use of this kind of antacid puts a high burdon on the kidneys
systemic antacids
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an example of a systemic antacid would be what?
sodium bicarbonate....baking soda
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this type of antacid is most useful for long term therapy, most of the dose remains in the GI tract, and does not alter acid base balance
non-systemic antacids
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prolonged use of compounds with aluminum hydroxide can cause ______ depletion
phosphate
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antacids containing these two salts cause constipation
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these drugs are considered non-systemic antacids
- Aluminum Carbonate Gel-Basaljel
- Ca Carbonate-Tums
- Dihydroxy-Al Na Carbonate-Rolaids
- magaldrate-riopan
- milk of mag
- mag oxide
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these drugs are used in the Tx of duodenal ulcers, gastric ulcers, and disorders that cause secretion of excessive stomach acid
H2 receptor antagonists
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these drugs inhibit the action of histamine at sensitive H2 receptor sites of parietal cells in stomach
H2 receptor antagonists
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side effects of H2 receptor antagonists are
- diarrhea
- muscle pain
- rash
- sleepiness
- dizziness
- confusion
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this is an H2 receptor antagonist that may have its effects decreased my smoking, it may also increase the effects of other drugs and is not to be give with antacids
Cimetidine-tagamet
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this H2 receptor antagonist may be given with antacids and is given once a day
Famotidine-Pepcid
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this H2 receptor antagonist is for heartburn and the pt should drink a full glass of water with medication....smoking interferes with drugs effects
nizatidine-axid
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this H2 receptor antagonist is not to be given with antacids, do not crush of chew these tablets...no alcohol, NSAIDS and salicylates
Ranitidine-Zantac
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these drugs are used for GERD and promote ulcer healing, relief of pain and decreases gastric acid production.....Tx of active duodenal ulcer
PPI-proton pump inhibitor
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these block the final step of acid production by inhibiting H, K, AT-pase system at secretory surface of gastric parietal cell...usually short term
PPI
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the side effects of these meds are headache, dizziness, pancreatitis, liver necrosis, hepatic failure, N/V, diarrhea
PPI
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this PPI drug is given before meals, and alcohol and OTC drugs should be avoided...short term use to prevent gastric tumors
omeprazole-prilosec
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this PPI drugs should be administered with or immediately after a mean....confusion may occur in the elderly or those with kidney or liver disease
raberprazole sodium- Aciphex
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while on this PPI drug you need to avoid alcohol and OTC products, and if unable to swallow capsule can be seperated
Esomeprazole-nexium
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this is a PPI drug and can be given with or w/o food
pantoprazole sodium-protonix
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this PPI med needs be be decreased if pt. has liver disease, and should be taken before meals...also avoid alcohol, ASA, NSAIDS and OTC
lansoprazole-prevacid
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these meds are used for duodenal ulcers, reflux and peptic esophagitis and are thought to form a barrier on the ulcer-adherent complex with albumin and fibrinogen at sire of ulcer to protect it from further damage by gastric acid
mucosal protectants
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this side effect of this type of medication is constipation
mucosal protectant
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this mucosal protectant is an antiulcer and is to be taken on an empty stomach and 30 min before or after antacids...do not crush or chew..no smoking, EOTH or caffine
sucralfate- Carafate
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this mucosal protectant is an antisecretory and inhibits gastric acid secretion...protects gastric mucosa by ^ bicarb and mucous production
Misoprostal-Cytotec
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these meds are used for symptomatic gastric reflux, prevention of N/V in cancer chemo therapy
-stimulate motility in the upper GI tract w/o stimulating production of gastric, biliary or pancreatic secretions
Prokinetic agent
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this drug increases peristalsis in duodenum and jejunum without increasing motility in lrg. intestine...relaxes pyloric sphincter... accelerates gastric emptying
prokinetic agent
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these drugs can cause CND depression, GI upset, Development of parkinsonism like reactions
prokinetic agent
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this drug is a prokinetic agent that cant be taken with EOTH or CNS depressants
Metoclopramide-Reglan, Maxolon
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these drugs are used to treat peptic ulcers prior to the discovery of safer drugs, and they have side effects such as dry mouth and constipation
- anticholinergic
- atropine
- gastrozepine-pirenzepine
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this is a synthetic form of prostaglandin that stimulates the production of protective mucus and inhibits gastric acid secretion
misoprostol-cytotec
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these are bulk forming laxatives
- fibercon-ca polycarbophil
- citrucel
- metamucil-naturacil
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these are saline and osmotic laxatives
- Milk of mag
- miralax-polythylene glycol
- sodium biphosphate-fleet
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these are stimulant laxatives
- bisacodyl-ducolax
- castor oil-emulsoil
- penolphthalein-ex lax
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this is a stool softener/surfactant
docusate-colace
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these drugs are antidiarrheal medications that are opiods
- paregoric
- motofen
- lomotil
- imodium
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this antidiarrheal drug can cause Reyes syndrome
bismouth subsalicylate-pepto, kaopectate
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