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Neuro #34 Basal nuclei clinical.txt
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What is
Hypokinetic disorder
?
Patient wants to perform an action but can't
What are two forms of
Hypkinetic disorder
?
1)
Akinesia:
no movement
2)
Bradykinesia:
movements are very slow
What pathways are affected by Hypokinetic disorders?
Both direct and indirect
What is
Hyperkinetic disorder
?
Patient performs action without wanting to perform the action
What pathway is affected by hyperkinetic disorder?
Indirect (can't inhibit)
What are three forms of
Hyperkinetic disorder
?
1)
ballism:
rapid, flinging movements
2)
Athetosis:
slow movements of limbs
3)
Chorea:
rapid, flailing movements of limbs (huntingtons disease)
What are the "kinesia" signs of Parkinson's disease?
Akinesia, bradykinesia, resting tremors
What specifically happens with the Basal Nuclei that causes
parkinson's
?
Pars Compacta of Substantia Nigra not producing Dopamine
**movements cannot be activated or enhanced
What is a "kinesia" sign of Huntingtons?
Chorea
What specifically happens with the
Basal Nuclei
that causes
Huntington's
?
Indirect pathway inhibited at level of striatopallidal axons.
Medium spiny neurons degenerate
What is a sign of
Tardive dyskinesia
?
Smacking of lips, chewing movements
What specifically happens with the Basal Nuclei that causes
Tardive dyskinesia
?
Hypersensitivity to Dopamine from Substantia Nigra
What is a sign of
hemiballismus
?
Ballism (rapid, flinging movements)
What specifically happens with the Basal Nuclei that causes
Hemiballismus
?
Subthalamic nucleus damage = indirect pathway inhibited = direct pathway always causing activity
Author
kepling
ID
79203
Card Set
Neuro #34 Basal nuclei clinical.txt
Description
Neuro #34 Basal nuclei clinical
Updated
2011-04-13T00:05:57Z
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