CNS Drugs

  1. Basic unit of the nervouse system.
  2. Chemicals synthesized in nerve cells that are released when stimulated.
  3. Chemical structure on the surface of a cell where certain molecules attach to produce an effect.
  4. Compound that binds to a specific receptor and produces a biological effect by stimulating the receptor.
  5. A drug that prevents natural substances from stimulating receptors by combining with the receptor but producing no effect.
  6. Excitatory neurotransmitters of the CNS
    • dopamine
    • seratonin
    • epinephrine
    • enkephalins
    • histamines
  7. Inhibitory neurotransmitters of the CNS
    • GABA
    • glycine
  8. Neurotransmitters of the PNS
    • ACH
    • Norepinephrine
    • Epinephrine
  9. Physical Element
    Level of stimulus needed to produce a painful sensation
    Similar in most people
    Pain Threshold
  10. Pyschological Element
    Amount of pain a person can endure without it interfering with normal function
    Pain Tolerance
  11. Sensation of pain
  12. Indications for Morphine
    • Mod-Severe pain
    • Medullary Cough
    • Diarrhea
  13. Side effects of Morphine
    • Lowers seizure threshold
    • Respiratory Depression
    • Rash, Itching
    • GI upset
    • Urinary retention
  14. What do yu treat a morphine OD with?
  15. Contraindications with Morphine
    Use caution with geriatrics because they metabolize meds slower
  16. Indications for acetaminophen
    • Analgesic
    • Antipyretic
  17. What is the mechanism of action for Acetaminophen?
    Interferes with prostaglandin and prevents synthesis
  18. Contraindications with acetaminophen
    Very harmful to liver because that is where it is metabolized. Should not consume with alcohol
  19. Indications for NSAIDs
    • Analgesic
    • Antipyretic
    • Antiinflammatory
  20. Side Effects of NSAIDs
    • GI upset because of prostaglandin
    • Bleeding
    • Renal impairment
  21. Symptoms of OD with NSAIDs
    • Tinnitus
    • Hypoglycemia
    • Electrolyte imbalance
  22. Considerations with NSAIDs and Children
    Do not give to children <16. Could cause Reye's Syndrome
  23. What drug treats seizure disorders?
  24. Side effects of Dilantin
    • Gingival hyperplasia
    • Slurred speech
    • Confusion
    • Thrombocytopenia
    • Leukopenia
  25. Which drug has a narrow therapeutic index of 10-20mcg/mL
  26. Nursing considerations for Dilantin
    • Teach good oral hygeine
    • Watch for bleeding/bruising
Card Set
CNS Drugs