Parm E3, V Hemostatic/Anticoagulants

Basic Process of Hemostasis (4):

Topical Hemostatics include (8):

Systemic Hemostatics include (2):

In Vitro Anticoagulants (4):

Anticoagulants used for transfusions (2):

Systemic Anticoagulants(2):

Vit K antagonists include (4):

Fibrinolytic Agents(4):

Anti-Platelet Drugs (4):

Thromboplastin converts ___ to ___

Admin of Thromboplastin:

Thrombin Converts ___ to ___

Clinical Uses of Thrombin (6):

Various Forms of Thrombin:

Admin of Thrombin:

Fibrinogen requires endogenous ____ to convert into Fibrin

Clinical Uses of Fibrinogen:

____ must be presoaked in thrombin sol

How do Fibrin Foams work?

Which product can absorb several times its weight in whole blood?

Which topical hemostatic is antigenic?

____ is applied to bleeding area, liquifies in 3-5 days and is absorbed in 4-6 weeks

Used as a Sx gauze/Sponge

Oxidized Cellulose is intended to be used as a tempory packing b/c it can interfere with:

Which Topical Hemostatic has a greater affinity for wet surfaces and adheres firmly?

Clinical Uses of Microcrystalline Collagen (2):

Topical Hemostatic that provides immediate vasoconstriction

Topical Hemostatic that acts as astringent

Which Topical Hemostatic can cause sloughing of tissue and hemorrhages?

Vit K aids in the production of which clotting factors?

Vit K Produces

Synthetic Analog of Vasopressin*

Functions of Desmopressin:*

Why does Vit K lose it's efficacy?

Anticoagulant that interferes with thrombin and fibrinogen:

What drug can be used to antagonise Heparine Induced Hemorrhagic Action

What drug has antithrombic and anticoagulatory properties?

Heparine Binds to ____, which induces a conformational change, which in turn inhibits ___ and activates ____

Heparine is metabolized by...

Clinical Uses of Heparin (5):

Anticoagulant Action of Vit K antagonists become evident after ___, and are present for ___

Where are Vit K Antagonists....
stored:
Metabolized:

Clinical Uses of Vit K Antagonists:

Fibrinolytic Agents are used to enhance the conversion of ____ to active ____

Duration of onset of streptokinase=

Which Fibrinolytic Agent selectively acts on fibrin clots?

Clinical Uses of Tissue plasminogen Activator

What drug is administered IP as a lavage to prevent adhesions in dogs?

Clinical Uses of Streptokinase (8):
Eczema
Dermatitis
Cellulitis
Hematomas
Trauma
Sinusitis
Cysts
Fractures w/ Fistulous Tracts

Clinical Use of Anti-platelet drugs (7):

Aspirin irreversibly inhibits ___, which inhibits ___

What potent aggregating factor is inhibited by aspirin

Ticlopidine is a ____ inhibitor

What drug is structurally related to Ticlopidine

Funciton of cAMP

What drugs inhibit cAMP?