-
Carbonic Anhydrase Inhibitors
-Carbonic _______ is an enzyme found in_______ and_______ which extracts water from carbonic acid.
-Inhibiting the enzyme will lead to excretion of _______ ,_______ , _______ .
-Used to treat _______ -angle (____ ___ ) not used in _______ angle.
- Carbonic Anhydrase Inhibitors
- -Carbonic
anhydrase is an enzyme found in kidney and lungs which extracts water from carbonic acid.- -Inhibiting the enzyme will lead to excretion of
na, k, hc03.- -Used to treat
open-angle (chronic glaumona) not used in narrow angle.
-
Carbonic Anhydrase Inhibitors
-Can be alternated with __________
-can cause __________, __________, __________.
-contraindicated in the _______________
Carbonic Anhydrase Inhibitors
- -Can be alternated with loop diuretics
- -can cause kidney stones, metabolic acidosis , crystalluria.
- -contraindicated in the first trimester of pregnancy
-
Potassium Sparing Diuretics
-_______ diuretics and can be used in combo with another _______ for max effect.
-_______ of potassium - doesn't require _______
-act on _______
-should be discontinued if serum k is _______
-Patient should put out at least _______
Potassium Sparing Diuretics
- -Mild diuretics and can be used in combo with another diuretic for max effect.
- -No loss of potassium - doesn't require supplement
- -act on collecting duct
- -should be discontinued if serum k is >5.3 mEq/L
- -Patient should put out at least 600ml/24hrs
-
Potassium Sparing Diuretics
-Prototype:________
-Acts by antagonizing ________
-takes up to ________ to act
-main side effect is________ -must be monitor
-must be used with caution in renal dysfunction
- Potassium Sparing Diuretics
- -Prototype:Aldactone
- -Acts by antagonizing aldosterone
- -takes up to 48 hours to act
- -main side effect is increase k -must be monitor
- -must be used with caution in renal dysfunction
-
Renal Failure and Diuretics
-The most commonly used drug in patients with ________ are diuretics.
-Other medications are used to manage some of the __________________
Renal Failure and Diuretics
- -The most commonly used drug in patients with renal dysfunction/failure are diuretics.
- -Other medications are used to manage some of the electrolyte imbalances
-
Contrast Neuropathy
-Currently, __________ is used to protect kidneys against the development of contrast induced __________
-__________ is an oxygen radial scavenger to prevent ischemic rperfusion injury.
-__________ are given beginning on the day prior to the procedure.
Contrast Neuropathy
- -Currently, Mucomyst is used to protect kidneys against the development of contrast induced nephrotoxicity
- -Mucoyst is an oxygen radial scavenger to prevent ischemic reperfusion injury.
- -4 doses are given beginning on the day prior to the procedure.
|
|
