-
penicillin
- strep
- enterococcus
- anaerobes (except for b. frag)
-
ampicillin
- strep
- enterococcus
- easy gm-
- anaerobes (except for b. frag)
-
amoxicillin
- strep
- enterococcus
- easy gm-
- anaerobes (except for b. frag)
-
-
piperacillin
- strep
- easy gm-
- hard gm- (including pseudomonas)
- anaerobes
-
pip/tazo (or ticar/clav)
- strep
- staph
- easy gm-
- hard gm- (including pseudo)
- anaerobes
-
1st gen cephalosporins (cefazolin, cephalexin)
- strep
- staph
- easy gm-
- ***NO CEPHS COVER ENTEROCOCCUS
-
2nd gen cephalosporins (cefuroxime)
- strep
- staph
- easy gm-
- anaerobes (except for b. frag)
-
3rd gen cephalosporins (cefixime, ceftriaxone, ceftazadime)
- easy gm-
- hard gm-
- pseudomonas by ceftazadime
- anaerobes
-
4th gen cephalosporins (cefipime)
- easy gm-
- hard gm-
- pseudomonas by cefipime
- anaerobes
-
carbapenems (IV only)
- strep
- staph
- easy gm-
- hard gm- (including pseudomonas)
- anaerobes (all)
-
-
clarithromycin
- strep
- staph
- easy gm- (H.influenzae ONLY)
-
azithromycin
- strep
- staph
- easy gm- (H.influenzae ONLY)
-
respiratory fluoroquinolones (moxifloxacin, levofloxacin)
- strep
- easy gm-
- hard gm- (NOT pseudomonas)
-
ciprofloxacin
- easy gm-
- hard gm-
- pseudomonas
-
AMG (gentamicin, amikacin, tobramycin)
- staph (synergy w/ B-lactam)
- MRSA (synergy w/ B-lactam)
- enterococcus (synergy w/ B-lactam)
- easy gm-
- hard gm-
- pseudomonas
-
-
tetracyclines
- strep
- staph
- easy gm-
- anaerobes (not b.frag)
-
vancomycin
- strep
- staph
- MRSA (DOC)
- enterococcus
- (only anaerobe = C. difficile in GIT)
-
TMP/SMX
- strep (but not A)
- staph
- easy gm-
-
-
linezolid
- strep
- staph
- MRSA (VRSA)
- enterococcus (VRE)
-
chloramphenicol
- strep
- easy gm-
- hard gm- (NOT pseudomonas)
- anaerobes
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