What are the 6 jobs of Immunoglobulins (B CAN MO)?
1) B-cell activation
2) Complement pathway (IgG and IgM bind to C1)
5) Mast Cell degranulation
What antibody participates in B-cell
What is the heterodimer that helps establish the mIg-BCR on B-cells?
Ig-Beta and Ig-Alpha
What receptor is expressed on a cell that needs to go through opsonization and phagocytosis?
FcReceptor (detects the bottom of the Y of the Ab)
What 5 cells participate in ADCC?
4) NK cells
For ADCC, what Ab signals NK cell attack?
What Ab particularly binds Helminths (parasites) and Mast cells?
Which is the most common IgG Ab: 1,2,3, or 4?
What fluid contains IgA Ab's?
Secretions (tears, saliva, etc.)
What does IgE bind to?
Mast Cells and Basophils
What two Ab serve as part of the BCR on Naive B-cells?
IgM and IgD