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Dilantin
Classification?
Therapeutic Level?
Adverse Effects?
Cautions?
Administration?
- Classification: Antiseizure
- Therapeutic level: 10-20
- Caution: with pregnancy, birth contro, can cause CV effects (dysrhythmia, hypotension - need cardiac monitor)
- Adverse effects: S-J syndrome, toxic epidermal necrosis
- Administration: no faster than 50 mg/min, must use inline micron filter. Can only be mixed with normal saline. Never mix with another drug.
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Tegretol
Classification?
Therapeutic level?
Adverse effects?
Cautions?
- Classification: Antiseizure
- Therapeutic level: 4-12
- Adverse effect: bone marrow suppression, SJ syndrome, epidermal necrosis
- Cautions: with pregnancy, take with food
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Depakote
Classification?
Therapeutic level?
Adverse effects?
Cautions?
- Classification: antiseizure
- Therapeutic level: 50-100
- Adverse effects: hepatotoxicity
- Cautions: with pregnancy
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Lamictal
Classification?
Therapeutic level?
Adverse effects?
Cautions?
- Classification: antiseizure
- Therapeutic level: 1-5
- Adverse effect: S-J syndrome, epidermal necrosis
- Cautions: with pregnancy
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Topamax
Classification?
Adverse effect?
Off label use?
- Classification: antiseizure
- Adverse effect: can cause closed-angle glaucoma - blindness!!!!
- Off label use: neuropathic pain
-
Valium and Ativan
Classification?
Use?
- Classification: antiseizure
- Use: SHORT TERM ACUTE episodes
Valium for STATUS EPILEPTICUS
-
Keppra
Classification?
Adverse effects?
- Classification: antiseizure
- Adverse effect: psychosis and hallucinations
-
Neurontin
Classification?
Adverse effects?
Off label use?
- Classification: anti-seizure
- Adverse effect: drowsiness and dizziness (DO NOT OPERATE HEAVY MACHINERY!)
- Off label use: pain
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Phenobarbitol
Classification?
Therapeutic level?
Adverse effetcs?
Cautions?
- Classification: anti-seizure
- Therapeutic level: 10-40
- Adverse effects: liver dysfunction, cognitive impairment
-
Decadron dexamethazone
Classification?
Use?
- Classification: corticosteroid
- Use: to decrease cerebral edema, brain tumors, and swelling
-
Mannitol
Classification?
Use?
Adverse effects?
Nursing implications?
- Classification: osmotic
- Use: for head injury, head bleed, before or during neuro surgery to draw free water from brain eliminated through kidneys
- Adverse effects: renal failure, CHF, pulmonary edema, hyper/hypokalemia, hyper/hyponatremia
- Nursing: monitor VS, CVP, resp status, urine output, neuro status, electrolyte imbalance
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Levodopa/Carbidopa (Sinemet)
Classification?
Effect?
- Classification: anti-parkinson
- Effect: levodopa crosses bbb. Carbidopa boosts effect of levodopa
-
Parlodel and Requip
Classification?
Use?
Side effect?
- Classification: anti-Parkinson
- Use: first agent used for younger patients before levodopa
- Side effect: postural hypotension
REQUIP: SUDDEN SLEEP EPISODES!
-
Artane and Cogentin
Classification?
Side effects?
- Classification: anticholinergic (for PD)
- Side effects: hypotension and urinary retention
-
Comtan and Tasmar
Classification?
Side effects?
- Classification: COMT Inhibitor (for PD)
- Side effects: neuroleptic malignant syndrome and hypotension
-
Eldepryl
Classification?
Adverse effect?
Avoid with?
Nursing implication?
- Classification: MAOB-I (for PD)
- Adverse effect: hypertensive crisis (220/110)
- Avoid with tricyclic antidepressants, SSRIs, Prozac, Demerol, foods with thyramine (aged chhese, cured meats, red wine)
- Nursing implication: increase fluid intake because can cause dry mouth
-
Tensilon
Use?
Have what available?
- Use: to diagnose Myesthenia Gravis - should have result in 30 seconds - relieve or muscle weakness and ptosis for 5 mins
- Have: Atropine available because can cause bradycardia
-
Mestinon
Classification?
Use?
Important to know?
Give what for overdose?
- Classification: anticholinesterase (for MG)
- Use: to increase muscle strength
- Important to know: give at regularly scheduled intervals before meals
- Give: Atropine for overdose
-
Imuran
Classification?
Adverse effect?
- Classification: cytotoxic agent (for MG)
- Adverse effect: hepatotoxic, immunosuppressant
-
Interferon
Classification?
Adverse effects?
- Classification: DMT (for MS)
- Adverse effect: immunosuppressant, causes flu-like symptoms
-
Copaxone
Classification:
Side effect?
- Classification: for MS
- Side effect: injection site reaction that should subside in 20 mins
-
Baclofen
Classification?
Side effect?
Cautions?
- Classification: anti-spasmotic (for MS)
- Side effect: drowsiness
- Caution: DON'T STOP ABRUPTLY - can cause paranoia, hallucinations, and RHABDO
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