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The national DNA database in the US has standardized _________ STRs for entry into the database.
13
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Recombinant DNA relies on the ability of chemicals known as __________ to cut DNA into fragments.
Restriction enzymes
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DNA is actually a very large molecule made of linking a series of _________ to form a natural polymer.
Nucleotides
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The short length of STRs allow them to be replicated by ________.
PCR (polymerase chain reaction)
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The structure of DNA requires the pairing of A to ___ and G to ____.
A-T, G-C
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A nucleotide is composed of a _______, a _________, and a ___________.
5 carbon sugar, nitrogenous base, and a phosphate.
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DNA fragments can be sorted according to their size by using ____________.
Electrophoresis.
-
The synthesis of new DNA from existing DNA is called __________.
replication
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A quantity of DNA is that is below the normal level of detection is known as ___________.
Low copy number.
-
_________ is a genetic locus useful for determining gender.
Amelogenin gene
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Whole blood collected for DNA typing purposes must be placed in a vacuum sealed container with the preservative ___________.
EDTA
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The typical STR DNA type emanating from a single individual will show a ___________ band pattern.
Double band pattern (two band)
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The base sequence TGCA can be paired with the sequence _________ in a double helix configuration.
ACGT
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In RFLP DNA typing, restriction enzymes are used to cut out sequences of DNA having different ___________.
lengths
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The inherited traits that are controlled by DNA arise out of DNA's ability to direct the synthesis of ________.
proteins
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The YSTR typing has utility when one is confronted with a mixture containing one or more _________ contributor(s).
Male
-
In RFLP DNA typing, DNA fragments are transferred to a nylon membrane by a process called ___________.
Southern Blot
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_________ is the process of joining two complimentary strands of DNA to form a double helix.
Hybridization.
-
CODIS, which stands for ________________, is the software maintained by the FBI.
Combined DNA Index System.
-
_________ and _________ techniques where used to identify 5 drops of blood at the crime scene to be that of OJ Simpson.
RFLP and PCR.
-
Watson and Crick demonstrated that DNA is composed of two strands coiled into a ___________.
double helix.
-
___________ are derived from a combination of up to 20 known amino acids.
Proteins
-
Each gene is actually composed of ___________ specifically designed to carry out a singlebody function.
DNA
-
DNA fragments can be separated and identified by __________.
capillary electrophoresis.
-
The amelogenin gene will show one band for a ___________ and two bands for a __________.
female, male.
-
Specimens amenable to DNA typing are __________, ___________, ____________, and ___________.
Blood, semen, body tissues, and saliva.
-
In RFLP DNA typing, a _________ labeled probe is used to visualize the separated DNA fragments.
Radioactive
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A ______ is a short strand of DNA used to target a region of DNA for PCR.
Primer.
-
________ is a procedure used to determine the order of the base pairs that comprise DNA.
DNA sequencing.
-
OJ Simpson's blood was found at the crime scene and is believed to have come from a wound that he had received to one of his _____________.
fingers
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Enzymes known as DNA _________ assemble new DNA into a proper base sequence during replication.
Polymerase
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Small amounts of blood are best submitted to a crime lab in a _________ condition.
Dry.
-
Short DNA segments containing repeating sequences of 3-7 bases are called
STRs.
-
_________ regions of mitochondrial DNA have been found to be highly variable in the human population.
2
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The concept of _________ involves the simultaneous detection of more than one DNA marker.
Multiplexing.
-
________ different bases are associated with the make up of DNA.
4.
-
Mitochondrial DNA is ______ plentiful in the human cell than nuclear DNA.
More.
-
YSTRs are located on the __ chromosome.
Y.
-
__________ are cells derived from the inner cheek lining.
Buccal
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The fundamental unit of heredity is the _____.
Gene
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The longer the DNA strand, the ________ susceptible it is to degredation.
More.
-
Mitochondrial is from _______
mom.
-
The production of AA is controlled by a sequence of 3 bases on the _________
DNA molecule
-
The probe has the sequence ____________
ATC
-
In RFLP,
Restriction enzymes are used to cut out repeating sequences.
-
PCR -
Polymerase Chain Reaction.
-
STR -
short tandem repeat
-
RFLP -
restriction fragment length polymorphism.
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An unstained object next to an area upon which biological material has been deposited is called a ___________.
substrate control.
-
Janitor who had the mental capacity of an 8 year old:
David Allen Jones
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Wrongfully convicted for raping a woman who later confessed she made it up due to domestic violence:
Gary Dotson
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Served 20 years doe a death sentence. recently had his case re..opened? :
Paul House
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Wrongfully convicted because was in the car of a murder rape victim. 24 years. :
Robert Clark
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Wrongfully convicted. 3-day trial. 24 years. :
Robert Clark
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Spent 35 years in prison for rape of a 13 year old when really his brother had raped her.
Arthur Murphrey
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Wrongfully convicted of raping a 38 year old & a 12 year old & tying them to trees :
Alan Cotzer
-
8 years in prison because evidence was illegally withheld. :
Kirk Bloodsworth
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Served 11 years of a life sentence for...of a 19 year old girl..due to a dream... :
Rolandro Cruz
-
Conviction overturned in 1994:
Earl Washington
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