Toxicology Exam 3

  1. Food aversion
    idiosyncratic avoidance of foods due to personal preferance
  2. Food intolerance
    • allergy
    • enzyme defect
    • pharmacological reaction
    • non-defined idiosyncratic responses
  3. Food poisoning
    • bacteria and viruses
    • molds
    • chemicals
    • toxins and irritants in foods
  4. General terms applied to a clinically abnormal response attributed to an ingested food or food additive
    adverse reaction (sensitivity) to food
  5. Adverse reaction to food with a proven immunologic basis
    food allergy (hypersensitivity)
  6. A general term describing an adverse reaction to food that does not have an immunologic basis
    Food intolerance
  7. An adverse reaction to food as a result of a naturally derived or added chemical that produces a drug like or pharmacologic effect in the host
    pharmacologic reaction to food
  8. an adverse reaction to food due to an effect of a substance upon the metabolism of the host, or as a result of defective metabolism of a nutrient by the host.
    metabolic reactions to food
  9. An adverse reaction to food caused by the direct action of a toxin
    food poisoning
  10. Food with highest incidence of allergy
  11. Sources of food allergies
    • restaurants (55%)
    • Packaged foods (28%)
    • Supermarkets (10%)
    • Delis (7%)
  12. Largest exposure to BPA comes from
    printed reciepts
  13. Tetrodotoxins come from
    puffer fishies
  14. Dimethylnitrosoamines come from ___ and causes ___
    • Bar-b-que
    • hepatic cancer
  15. Unsuspected food toxins
    • peach seeds
    • clams
    • oysters
    • fish roe
    • sushi
  16. Fish Roe may cause toxicity because of
    high fat content that stores toxins
  17. Caused by consumption of shellfish (raw or cooked oysters, clams, mussles) or broth from cooked shellfish that contain marine toxins elaborated by the plankton upon which shellfish feed
    paralytic shellfish poisoning (PSP)
  18. symptoms of PSP
    • develope within 2-18 hours of ingestion
    • neurological symptoms
  19. symptoms of PSP include
    • tingling, burning or numbness of the face or extremities
    • drowsiness
    • incoherent speech
    • muscle paralasis/respiratory failure in severe cases
  20. Toxin that causes PSP is ____x more potent than CN
  21. PSP diagnosis
    laboratory confirmation by mouse bioassay of suspect food
  22. Other diagnosis to rule out when considering PSP
    • pesticide exposure
    • botulism
    • ciguatera fish poisoning
  23. Treatment for PSP
    • supportive
    • close respiratory monitoring
    • anticholinesterases are not recommended
  24. PSP is considered to be a
    rare disease of publich health importance
Card Set
Toxicology Exam 3
Food Toxicology