-
Amiodarone(Cordarone)
- Class:
- Antiarrythmics (class III), used to prevent sudden cardiac death (VF)
- Prolongs action potential & refractory period,
- Inhibits adrenergic stimulation, Slows sinus rate, increases PR & QT
- intervals & decreases PVR, vasodilates
PO 100-400mg/day for maintenance
- SE: hypotension,
- bradycardia, pulmonary fibrosis, CHF, worsening of arrhythmia, dizziness,
- fatigue, malaise, corneal micro deposits, blue discolartion of skin,
- hypothyroidism, ataxia, involuntary movement, paresthesia, peripheral
- neuropathy, tremor
Teach: Avoid grapefruit juice,
BP HR
-
Carvedilol(Coreg)
- Class:
- Antihypertensive/Beta Blocker; Used in HTN, or HF, irreg heart rhythms
- Blocks Beta1 and 2 adrenergic receptor sites
- improving CO, decreasing BP and HR. Blocks some alpha 1 activity which can
- result in OH
PO: 6.25-25 mg bid
- Dizziness, bradycardia
- fatigue, weakness, , CHF, Pulmonary edema, diarrhea, dont Abrupt w/d masks
- hyper/hypoglycemia, bronchospasm
- Teach:
- Change position slowly to avoid OH, Monitor BG in DM
- BP ___________
- P__________ BG _________if DM
-
Digoxin (Lanoxin)
- Class:Antiarrhythmics/inotropes/digitalis
- glycoside; used in HF, & irreg heart rhythms
- Increases force of myocardial contraction. Prolongs
- refractory period of the AV node. Decreases conduction through the SA and AV
- nodes
PO: 0.125-0.25mg/day
- SE & toxicity signs: bradycardia, Fatigue, headache, weakness, blurred vision, yellow or green
- vision, arrhythmias, ECG changes, A-V block, S-A block, anorexia, N&V,
- diarrhea, gynecosmastia, thrombocytopenia, e-lyte imbalances, acute digoxin
- toxicity
- Teach:
- Review s/s of toxicity and advise to report immediately, Do not mix in
- container with other meds
HR
-
Enalapril (Vasotec)
- Class:
- Antihypertensives/ACE inhibitors; used in htn, hf
- Blocks the conversion of angiotenson I to
- angiotenson II causing vasodialation.
- Prevents degradation of bradykinin and other vasodilatory prostoglandins
PO: 2.5-5mg/day
- SE: hypotension,
- Dizziness, fatigue, headache, weakness, vertigo, chronic cough, chest pain,
- abd pain, diarrhea, N&V, proteinuria, impaired renal func, rash,
- hyperkalemia, dyspnea, angioedema
- Teach:
- Do not d/c unless directed by DR, Avoid salt sub containing K+ and foods high
- in K+.
- Change position slowly to avoid OH, Notify Dr
- immediately of swelling of face or tongue
BP HR K
-
Furosemide (Lasix)
- Class:
- Diuretics/loop diuretics; used to tx edema & CHF
Inhibits reabsorb of Na and Cl- in kidney
- Increases renal excretion of H2O, Na, Cl-, Mg, K+
- and Ca++
PO: 20-80mg/day
- Side effects: Dehydration, hypokalemia,
- hypomagnesemia, hyponatremia, hypov olemia,
- dizziness, vertigo, headache, hypotension, polyuria, hyperglycemia
- Teach:
- Daily wts, notify Dr of cramping, tachycardia, dizziness, increased fall risk,
- rise slowly
-
Heparin
- Class:
- Anticoagulants/antithrombotics---prevent DVTs
- Potentiates the inhibitory effect of antithrombin
- on factor X and thrombin
SC: 5000 units/tid
- SE: Drug-induced hepatitis, alopecia, bleeding,
- anemia, thrombocytopenia, osteoporosis, fever, hypersensitivity, pain at
- injection site, rash, urticaria
- Teach:
- Report s/s of unusual bleeding/bruising, No asa or NSAIDS, Avoid IM
- injections(IV Route), Use soft toothbrush and electric razor
- PTT (IV route)
- platelets:
-
Hydralazine (Apresoline)
- Class:
- Antihypertensive/vasodilator, used in htn & HF
Direct-acting peripheral arteriolar vasodilator
PO: 10-50mg
- SE: Dizziness, drowsiness, headache,
- tachycardia, angina, arrhythmia, edema, OH, diarrhea, N&V, rashes, Na
- retention, arthritis, peripheral
- neuropathy,
- Teach:
- Take even if feeling well, Take at same time daily, Don’t abruptly stop taking,
- Compliance with Htn interventions, Change position slowly to avoid OH, Report
- generalized tiredness, fever, muscle/joint pain, rash, chest pain
- BP ____________
- P _____________
-
Hydrochlorothiazide (HCTZ)
- Class:
- Antihypertensive/Diuretics: used in htn
- Increases excretion of Na and H2O by inhibiting Na
- reabsorption in distal tubule. Promotes
- excretion of K+, H+, Mg, Ph, Ca++ and Bicarb.
- May produce arteriolar dilation
PO: 12.5-100mg/day
- SE: Dizziness, drowsiness, lethargy,
- weakness, hypotension, anorexia, N&V, photosensitivity, dehydration,
- hypercalcemia, hypokalemia, hypomagnesemia, hyponatremia, hypovolemia,
- hypophosphatnemia
- Teach:Take
- same time every day, Monitor wt biweekly, Change position slowly to avoid OH
Wt trending BP HR K
-
Isosorbide Mononitrate (IMDUR) (Nitrate)
- Class:
- Venodialators/antianginals/nitrates: used in CAD
- Vasodilation, Decreases LVED pressure and preload,
- Increases coronary blood flow, reduces myocardial O2 use
- Usual dose
- range 30-60mg/day can not be crushed
- Side effects: Dizziness, headache, hypotension,
- tachycardia, paradoxic bradycardia, syncope, N&V, flushing, tolerance
- Teach:
- Take even if feel better, Take daily doses 7hr apart, Avoid alcohol, Inform Dr
- of dry mouth or blurred vision
Change position slowly to avoid OH
- BP ____________
- P _____________
-
Lisinopril (Prinivil)
- Class:
- antihypertensive/ACE Inhibitor; used htn, HF
- Blocks the conversion of angiotenson I to
- angiotenson II causing vasodialation.
- Prevents degradation of bradykinin and other vasodilatory prostoglandins
- ****decreases remodeling
PO 5-10mg/day may be titrated to 40mg/day
- SE: Dizziness, fatigue, headache, weakness,
- chronic cough, hypotension, chest pain, abd pain, diarrhea, nausea, vomiting,
- ED, impired renal func, rashes, hyperkalemia, angioedema
- Teach:
- Do not d/c unless directed by DR, Avoid salt sub containing K+ and foods high
- in K+
- Change position slowly to avoid OH, Notify Dr
- immediately of swelling of face or tongue
BP HR K
-
Losartan (Cozaar)
- Class:
- Antihypertensive/ Angiotension
- receptor blocker (ARB) (lowers BP
- & used in HF)
- Blocks vasoconstriction and aldosterone secreting
- effects of angiotensin ii at various receptor sites; used in htn & heart
- failure
Usual dose range: 25-100 mg/day
- Side effects: Dizziness, fatigue, headache, insomnia,
- weakness, chest pain, edema, hypotension, diarrhea, angioedema, hyperkalemia,
- impaired renal function
- Teach: Change
- position slowly to avoid OH
- BP ____________
- P _____________ K+
- ___________
-
Metolazone (Zaroxolyn)
- Class:
- Antihypertensive/thiazide like diuretic, used to tx edema & CHF
- Increase excretion of Na by preventing reabsorbtion
- in distal tubule. Promotes excretion of Cl-, K+, Mg and bicarb. May arteriolar dialate.
PO: 2.5-5 mg/day
- SE: Chest pain, hypotension,
- palpitations, anorexia, dehydration, hypochloremia, hypokalemia,
- hypomagnesemia, hyponatremia, hypovolemia, muscle cramps
- Teach:
- Take same time everyday, Monitor wt daily, Change position slowly to avoid OH,
- Wear sunscreen(d/t poss photosensitivity)
-
Metoprolol (Lopressor)
- Class:Antihypertensive/Beta
- Blockers Used in HTN, or HF, irreg heart rhythms
- Blocks stimulation of beta1(myocardial)-adrenergic
- receptors. Does not usually affect beta2(pulmonary, vascular, uterine )
- adrenergic receptor sites.
PO: 25-450mg/day
- Side effects: bradycardia, Fatigue,
- weakness, CHF, pulmonary edema, ED, hypo/hyperglycemia, bronchospasm, wheezing,
- hypotension, peripheral vasoconstriction, constipation, diarrhea, joint pain,
- nightmares
- Teach:
- Do not abruptly withdrawl, Change
- position slowly to avoid OH, Notify Dr of slow HR, wheezing & dyspnea
- BP ___________
- P__________ BG _________ if DM
-
Spironolactone (Aldactone)
- Class:
- K+ sparing diuretics
- Causes loss of Na Bicarb and Ca++ while saving K+
- and H+ ions by antagonizing aldosterone; used to tx edema & CHF
PO: 25-400 mg/day /CHF use 12.5-25 mg/day
- SE: Dizziness,
- hyperkalemia, hyponatremia, gynecomastia, ED, dysuria, arrythmias, headache, GI
- irritation, muscle cramps
- Teach:
- Avoid salt substitutes and high levels of K+ unless prescribed
Wt trending BP HR K
-
Amlodipine (Norvasc)
- Class:
- Antihypertensives/Calcium channel blockers
- Inhibits transfer of ca++ into myocardial &
- vascular smooth muscle cells resulting in inhibition of excitation contraction
- coupling & subsequent contraction.
- Systemic vasodilation resulting in i
- BP.
- PO Adults: 5-10mg once daily;
- antihypertensive in fragile or smaller patients or patients already receiving
- other antihypertensives – initiate at 2.5mg/day - h as required/tolerated (up to 10mg/day).
- PO Geriatric: Initiate at 2.5mg/day - h as reqd/tolerated (up to 10mg/day). Anti-anginal – initiate at
- 5mg/day - h as reqd/tolerated (up to 10mg/day).
- SE:
- Headache, dizziness, fatigue; peripheral edema, angina,
- bradycardia, hypotension, palpitations;
- gingival hyperplasia, nausea, flushing.
- Teach:
- Take as directed; take missed dose ASAP but DO NOT double dose. Avoid large amounts of grapefruit juice (6-8
- glasses/day) during therapy.
BP________P_________
-
Labetalol (Trandate)
- Class:
- Antianginals, antihypertensives/beta blockers
- i BP. Blocks
- stimulation of beta1 (myocardial)-
- and beta2 (pulmonary, vascular, and
- uterine)-adrenergic receptor sites. Also
- has alpha1-adrenergic blocking
- activity, which may result in more orthostatic hypotension.
- PO: 100 mg bid initially, may be h by 100 mg bid q 2-3 days as needed (usual range 400-800 mg/day in
- 2-3 divided doses; doses up to 1.2-2.4g/day have been used.)
- SE:
- Fatigue, weakness, anxiety, depression dizziness, drowsiness, insomnia;
- OH, arrhythmias, bradycardia, CHF, pulmonary edema; constipation, diarrhea,
- nausea.
- Teach:
- Take as directed at the same time each day, even if feeling well; take
- missed dose ASAP up to 8 hr. before next dose – DO NOT double dose. Abrupt withdrawal may precipitate life
- threatening arrhythmias, hypertension, or myocardial ischemia. May cause
- dizziness – do not drive/operate heavy machinery until response to medicine is
- known. Change positions slowly to avoid
- OH. Notify healthcare professional if
- slow pulse, difficulty breathing, wheezing, cold hands and feet, dizziness,
- light-headedness, confusion, depression, rash, fever, sore throat, unusual
- bleeding or bruising occurs.
-
Folic acid (Apo-Folic, folate, Folvite, Novofolacid, vitamin B)
- Class:
- Antianemics, vitamins/water soluble vitamins
- Required for protein synthesis and red blood cell
- function. Stimulates the production of RBCs, WBCs, and platelets. Necessary for
- normal fetus development. Restoration
- and maintenance of normal hematopoiesis
- PO, IM, IV, SubQ: 1 mg/day initial dose,
- then 0.5 mg/day maintenance dose.
- SE:
- Rash, irritability, difficulty sleeping, malaise, confusion, fever.
- Teach:
- folic acid in early pregnancy is necessary to prevent neural tube defects; high
- folic acid foods include vegetables, fruits, and organ meats; heat destroys
- folic acid in foods; instruct patient to notify health care profession if rash
- occurs, which may indicate hypersensitivity.
Hbg Hct
-
Metronidazole (Flagyl)
- Class:
- Anti-infectives, antiprotozoals, antiulcer agents.
- Disrupts DNA and protein synthesis in susceptible
- organisms. Most notable for activity
- against anaerobic bacteria, including Bacteroides,
- Clostridium. In addition is active
- against Trichomonas vaginalis, Entamoeba
- hystolytica, Giardia lamblia, H. pylori, Clostridium difficile.
- PO: Anaerobic infections 7.5 mg/kg q 6 hr
- (not to exceed 4g/day) initial dose, then 0.5 mg/day maintenance dose.
- SE:
- Seizures, dizziness, headache, aseptic meningitis (IV), encephalopathy
- (IV), abdominal pain, anorexia, nausea, diarrhea, Stevens-Johnson Syndrome,
- rash, urticaria.
- Teach:
- Take medication as directed with evenly spaced time between doses, even if
- feeling better. Do not skip doses or
- double up. May cause dizziness or
- lightheadedness. May cause unpleasant metallic taste.
-
Minoxidil
- Class:
- Antihypertensives/vasodilators
- Directly relaxes vascular smooth muscle, probably
- by inhibiting the enzyme phosphodi-esterase. Results in vasodilation, which is
- more pronounced in arterioles than veins. i
- BP.
- Used in severe symptomatic hypertension or hypertension
- with end-organ damage that has failed to respond to combinations of more
- conventional therapy.
- PO: 5 mg once daily or in 2 divided
- doses; may double at 3-day intervalsl usual range 10-40 mg/day (for rapid
- control with careful montoring, doses may be adjusted q 6 hrl up to 100 mg/day
- have been used).
- SE:
- HA; pulmonary edema; CHF, ECG changes, tachycardia, angina, pericardial
- effusion; nausea; hypertrichosis, rashes; sodium and water retention;
- intermittent claudication.
- Teach:
- Continue this medication even if feeling well; take missed doses as soon
- as re-membered if within a few hours; otherwise omit dose, DO NOT double dose;
- do not D/C without physician approval; encourage proper diet and regular
- exercise; change positions slowly to avoid OH; NSAISs may i
- the AH effectiveness. BP P
-
Diltiazem Hydrochloride
(Cardizem)
- Inhibits
- influx of calcium through the cell membranes, resulting in a depression of
- automaticity and conduction velocity in cardiac muscle. Decreases SA and AV
- conduction and prolongs AV node effective and functional refractory periods.
PO 120 mg or 180 mg
- S/E AV block, bradycardia, edema, dizziness/lightheadedness, HA,
- pain, dyspnea, rhinitis, infection.
- Teach:
- Take at same time each day, Rise slowly from a lying to a sitting and standing
- position; may cause decreased BP.
BP P
-
Pentoxifylline (Pentoxil, Trental)
- Class: Blood viscosity reducing agent;
- used in management of symptomatic PVD (intermittent claudication)
- Increases the flexibility of RBC’s by increasing
- levels of cyclic adenosine monophosphate (cAMP). Decreases blood viscosity by inhibiting
- platelet aggregation and decreasing fibrinogen.
- PO: (Adults)
- 400 mg tid. If GI or CNS S/E occur, i dose to 400 mg bid.
- SE:
- Agitation, dizziness, drowsiness, headache, insomnia, nervousness, blurred
- vision, dyspnea, angina, arrhythmias, edema, flushing, hypotension, abdominal
- discomfort, belching, bloating, diarrhea, dyspepsia, flatus, nausea, vomiting,
- tremors.
- Teach: Instruct pt. to
- take medication as directed, consult healthcare provider before d/c or if
- nausea, vomiting, GI upset, drowsiness, or headache persists; to avoid driving
- as dizziness & blurred vision may occur; avoid smoking, as nicotine
- constricts blood vessels.
BP
-
Ranolazine (Ranexa)
- Class: Antianginals, used
- for chronic angina to decrease frequency
PO: 500mg BID, may be á to 1000mg BID, do not break, crush, or chew
- SE: dizziness, headache, tinnitus, palpitations, abdominal pain,
- constipation, dry mouth, N&V
- Teach: If miss a dose, take next
- dose at usual time, do not double doses, Avoid grapefruit juice and grapefruit
- products, Avoid driving and activities until side effects are known, Consult
- provider before taking other Rx, OTC, or herbal products
- Assess: location, duration,
- intensity, and precipitating factors of angina pain
- BP__________
- HR _________
-
Nitroglycerine (Nitrostat)
- Class:
- Antianginals/nitrates
- Vasodilation; i
- LVED pressure and preload; h coronary blood flow;
- reduces myocardial O2 use.
- SL: 0.3-0.6 mg - may repeat q5 min 2
- additional doses for acute attack
PO: 2.5-9 mg q8-12 hours
- SE: Dizziness, headache, hypotension, tachycardia, syncope, blurred
- vision, weakness, apprehension, restlessness.
- Teach:
- Do not abruptly d/c; Change position slowly to avoid OH; Call 911 or go to ER
- if 3SL/15 min not effective (home use instruction); Avoid alcohol consumption.
BP HR P ECG
-
Warfarin (Coumadin)
- Class:
- Anticoagulant/coumarin
- Interferes with hepatic synthesis of vitamin
- K-dependent clotting factors.
- PO, IV: 2.5-10 mg/day – Adjusted based on
- PT INR
SE: Cramps, N & V, dermal necrosis, bleeding, fever.
- Teach:
- Avoid alcohol, NSAIDs, ASA. Review foods
- high in vitamin K and keep amount consistent.
- Avoid IM injection. Frequent lab
- monitoring. Bleeding precautions.
PT INR
-
Levothyroxine (Synthroid)
- Class:
- Hormones/thyroid preparations
- Replaces or supplements endogenous thyroid
- hormones. h
- metabolic rate of body tissues.
PO: 75-125 mcg/day (1.5mcg/kg/day)
IM, IV: 50-100mcg/day as single
- SE:
- Insomnia, irritability, headache, arrhythmias, tachycardia, angina
- pectoris, abd. cramps, diarrhea, vomiting, hyperhydrosis, hyperthyroidism,
- menstrual irregularities, wt. loss, heat intolerance.
- Teach:
- Take same time each day; Explain therapy is not cure, lifelong; Notify Dr. of
- unusual s/s; Do not take within 4 hrs. of iron or ca++ consumption; Periodic
- labs.
TSH HR
-
Thiamine (Biamine)
- Class:
- Vitamins/water soluble vitamins
Required for carbohydrate metabolism.
PO: 5-10 mg/tid / IM, IV: 5-100 mg tid.
- SE:
- Restlessness, weakness, tightness of throat, pulmonary edema,
- respiratory distress, vascular collapse, hypotension, vasodilation, GI
- bleeding, angioedema, nausea, cyanosis.
- Teach:
- Encourage dietary compliance; Teach about foods high in thiamine; Caution about
- OTC vitamin supplements and teach RDA.
-
Potassium chloride (K-Dur)
- Class:
- Mineral and electrolyte replacement/supplement
Prevention of K depletion;
- Usual dose
- range 20-40 mEq/day in 1 – 2 divided doses. Single dose not to exceed 20 mEq
- Side effects: Abdominal pain, diarrhea, flatulence, nausea,
- vomiting, confusion, restlessness, weakness, arrhythmias, ECK changes.
- Teach:
- Take missed doses as soon as remembered within 2 hours; Do not double dose;
- Report dark, tarry, or bloody stools; weakness, unusual fatigue, or tingling of
- extremities; Notify Dr. of persistent nausea, vomiting, diarrhea, or stomach
- discomfort.
K _____________
-
Tolterodine (Detrol)
- Class:
- Urinary tract antispasmodic/anticholinergic
- PO: 2 mg as
- tablets bid may be lowered depending on response or 2-4 mg once daily as
- extended release capsules.
- Side effects: Headache, dizziness, blurred vision, dry
- eyes, dry mouth, constipation, dyspepsia.
- Teach:
- Instruct to take as directed; May cause dizziness and blurred vision – avoid
- driving and other activities requiring alertness until effect is known.
Monitor liver function. (in long term therapy
-
Citalopram (Celexa)
DO NOT CONFUSE WITH CELEBREX
- Class:
- Antidepressant/selective serotonin reuptake inhibitors (SSRI’s)
Used for depression.
- PO: 20 mg
- daily initially. May be h by 20 mg at weekly intervals, up to 60
- mg/day (usual dose is 40 mg/day).
- Side effects: Apathy, confusion, drowsiness, insomnia,
- weakness, abdominal pain, anorexia, diarrhea, dry mouth, dyspepsia, flatulence, h saliva, nausea, sweating, tremors; neuroleptic malignant
- syndrome, suicidal thoughts.
- Teach:
- Instruct to take as directed; avoid alcohol; change positions slowly to
- minimize dizziness; Instruct patient not to take within 14 days of MAO
- inhibitors
-
Pantoprazole (Protonix)
- Class:
- Antiulcer agent/proton-pump inhibitors
- Prevention of stress ulcers. Diminished accumulation of acid in the
- gastric lumen, with lessened acid reflux.
- PO: GERD - 40 mg once daily; Gastric
- hypersecretory conditions – 40 mg bid up to 120 mg bid.
- SE:
- Headache, abdominal pain, diarrhea, eructation, flatulence,
- hyperglycemia.
- Teach:
- Take as directed; Take full course of therapy even if feeling better; avoid
- alcohol; products containing NSAIDs & ASA; Report dark, tarry stools;
- diarrhea, or abdominal pain.
Bilirubin AST ALT Alkaline phosphatase (in long term use only)
-
Simvastatin (Zocor)
- Class:
- Lipid lowering agent/Hgb CoA reductase inhibitors
- 2° prevention of cardiovascular events (i
- risk of MI, coronary revascu-larization, stroke, and cardiovascular mortality)
- in patients with clinically evident CHD or those at risk for CHD (Hx of
- diabetes, PAD, or stroke).
PO: 5 - 80 mg once daily in the evening.
- SE:
- Dizziness, headache, insomnia, weakness, chest pain, peripheral edema,
- rhinitis, lovastatin, blurred vision, bronchitis, abdominal cramps,
- constipation diarrhea, flatus, heartburn, nausea, rashes, hypersensitivity
- reactions.
- Teach:
- Take as directed; Advise patient that this medicine should be taken in
- conjunction with diet restriction.
- Notify Dr. of unexplained muscle tenderness, pain, weakness, fever, or
- malaise.
- Serum cholesterol Triglyceride Liver
- function-AST
-
Aspirin (Acetylsalicylic acid, Acuprin, ASA, Aspirtab, Bayer, Ecotrin)
- Class:
- Antipyretics, Non-opioid analgesics/Salicylates
- i platelet aggregation. i
- inflammation & fever by inhibiting the production of prostaglandins.
PO: 80-325mg once daily.
- SE:
- Tinnitus (ringing in ears), GI BLEEDING, dyspepsia (indigestion),
- epi-gastric distress, nausea, abdominal pain, anorexia, hepatotoxicity,
- vomiting, anemia, hemolysis, rash,
- urticaria (hives), anaphylaxis &
- laryngeal edema.
- Teach:
- Take w/full glass of water and remain upright for 30 min after administration. Report tinnitus, unusual bleeding of gums,
- bruising, black tarry stool, or fever
- > 3 days. AVOID USING ALCOHOL,
- ACETA-MINOPHEN, OR NSAIDs W/ THIS MED.
- Reduce sodium intake.
-
Clopidogrel (Plavix)
- Class:
- Antiplatelet agents/platelet aggregation inhibitors
- Inhibits platelet aggregation by irreversibly
- inhibiting the binding of ATP to platelet receptors. i
- occurrence of atherosclerotic events in patients at risk
PO: 75mg once daily.
- SE:
- GI BLEEDING, NEUTROPENIA, THROMBOTIC THROMBOCYTOPENIC PUPURA, depression,
- dizzy, fatigue, HA, epistaxis, cough, dyspnea, chest pain, edema, HTN,
- abdominal pain, diarrhea, dyspepsia, hypercholesterolemia, back pain, fever,
- hypersensitivity reactions.
- Teach:
- Take exactly as directed. Take missed
- dose ASAP unless almost time for next dose; DO NOT double dose. Notify physician if fever, chills, sore
- throat, unusual bleeding or bruising occurs.
- Contact physician before taking Rx, OTC or Herbal products especially
- those containing ASA, NSAIDs, or proton pump inhibitors.
- Monitor renal function & Neuro. CBC
- Platelet
-
Clonidine
(Catapres)
- Class:
- Antihypertensive/adrenergic; used in HTN, cancer pain
- unresponsive to opioids alone
- Stimulates alpha-adrenergic
- receptors in CNS resulting in decreased sympa-thetic outflow (HTN); this also
- prevents pain signal transmission to CNS.
- PO: 0.1mg bid to start, increasing to maintenance dose of 0.2-0.6
- mg/day
- S/E: drowsiness,
- depression, dizziness, nervousness, nightmares, bradycardia, hypotension,
- palpitations, dry mouth,
- constipation,
- N & V, ED, rash,
- sweating, Na+ retention, wt gain, withdrawal
- phenomenon
- Teach:
- Take at same time each day, change position slowly to avoid OH, freq mouth
- rinses, good oral hygiene and sugar-free gum can help with dry mouth
BP________ P_________
-
Tamsulosin (Flomax)
- Class:
- Peripherally acting antiadrenergic
- i
- symptoms of prostatic hyperplasia (urinary urgency, hesitancy, nocturia).
- i contractions of smooth muscle of prostatic capsule
- by preferentially binding to alpha, -adrenergic receptors.
- PO: 0.4 mg/daily after a meal; may be h after 2-4 weeks to 0.8mg/day.
- DO NOT open, crush, or chew.
- SE:
- Headache, dizziness; rhinitis; OH.
- Teach:
- Take as directed; Take full course of therapy even if feeling better; take at
- same time each day. May cause dizziness
- – do not drive/operate heavy machinery until response to medicine is
- known. Change positions slowly to avoid
- OH.
I/O BP
-
Hydrocodone/acetaminophen
(Vicodin)
- Class:
- Opioid analgesic/opioid agonists; non-opioid analgesic combinations
- Binds to receptors in the CNS. Alters perception of, and response to,
- painful stimuli while producing generalized CNS depression.
- i
- in severity of moderate pain, suppression of cough reflex
- PO: 2.5-10mg q3-6h as
- needed. Acetaminophen dosage should not
- exceed 4g/day. (Ibuprofen products
- should not exceed 5 tablets/day.)
- S/E: Confusion, dizziness,
- sedation; hypotension; constipation, dyspepsia, nausea, vomiting, urinary
- retention, sweating.
- Teach:
- Take as directed, do not take more than recommended amount. Teach patient to turn, cough, and deep breath
- q2hr to prevent atelectasis.
- May cause h
- plasma amylase and lipase concentrations in long term use
-
Famotidine (Pepcid)
- Class:
- Anti-ulcer agent/Histamine H2 antagonist.
- Inhibits the action of histamine at the H2 receptor
- site located primarily in gastric parietal cells, resulting in inhibition of
- gastric acid secretion. Healing and
- prevention of ulcers.
- PO: 40 mg/day HS or 20mg bid for up to 8
- weeks.
- SE:
- Confusion, dizziness; drowsiness, hallucination, headache; arrhythmias;
- constipation diarrhea, nausea; agranulocytosis; aplastic anemia.
- Teach:
- Take as directed; Take full course of therapy even if feeling better; take
- missed dose ASAP but DO NOT double dose.
- Report to physician onset of black, tarry stools, fever, sore throat,
- diarrhea, dizziness, rash, confusion, or hallucinations.
CBC w/differential in long term use
-
Docusate (Colace, Dulcolax, Correctol)
- Class:
- Laxatives/Stool softeners
- Promotes incorporation of water into stool,
- resulting in softer stool mass.
PO: 50-400mg in 1-4 divided doses.
- Rectum: 50-100mg or 1 unit containing
- 283mg docusate sodium, soft soap, and glycerin.
- SE:
- Throat irritation; mild cramps, rashes.
- Teach:
- Laxatives should be used only for short term therapy. Encourage patient to use other forms of
- therapy such as h bulk in diet, h
- fluid intake (6-8 glasses of water daily), h
- mobility. Instruct patients with cardiac
- disease to avoid straining during a BM (Valsalva maneuver). Do not take within 2 hours of other
- laxatives.
Please hold if not needed
-
Amlopidine (Norvasc)
- Class:
- Antihypertensives/Calcium channel blockers
- Inhibits transfer of ca++ into myocardial &
- vascular smooth muscle cells resulting in inhibition of excitation contraction
- coupling & subsequent contraction.
- Systemic vasodilation resulting in i
- BP.
- PO Adults: 5-10mg once daily;
- antihypertensive in fragile or smaller patients or patients already receiving
- other antihypertensives – initiate at 2.5mg/day - h as required/tolerated (up to 10mg/day).
- PO Geriatric: Initiate at 2.5mg/day - h as reqd/tolerated (up to 10mg/day). Anti-anginal – initiate at
- 5mg/day - h as reqd/tolerated (up to 10mg/day).
- SE:
- Headache, dizziness, fatigue; peripheral edema, angina,
- bradycardia, hypotension, palpitations;
- gingival hyperplasia, nausea, flushing.
- Teach:
- Take as directed; take missed dose ASAP but DO NOT double dose. Avoid large amounts of grapefruit juice (6-8
- glasses/day) during therapy.
- BP________P_________
- ECG_________
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