COX inhibitors may only be used for pain management with which agent?
CCBs (it is contraindicated for all other groups)
stroke, MI, and hypertension are effects of _______ levels
cholesterol
the total cholesterol level in a healthy patient will be < ______ mg/dl
200
LDL should be < ______mg/dl to be healthy
130
HMG-CoA reductase inhibitors are used to _______ ________
lower cholesterol
which inhibitor is referred to a "statins"?
HMG-CoA reductase inhibitors
lipitor, zocar, restor, and lescol are all which type of agent?
lipid-lowering agents
how do lipid-lowering agents work?
they interfere with cholesterol synthesis in the liver
cholestyramine, colesevelam, and colestipol are all ______ ______sequestrants
bile acid (lipid-lowering agents)
what is the mechanism of action of bile acid sequestrants (cholestyramine, colesevelam, colestipol)?
agents bind with bile in intestine and form insoluble complex
bile acid sequestrants may be used in combination with ________ ________ inhibitors
HMG-CoA reductase inhibitors
what are used to lower cholesterol and tryglycerides and increase HDL levels?
fibric acid derivatives
lopid and tricor are both ______ _______ derivatives
fibric acid
what is the mechanism of action inhibits synthesis and increase clearance of LDLs and reduce triglycerides by decreasing hepatic extraction of free fatty acids?
fibric acid derivatives
HMG-CoA reductase inhibitors
Bile acid sequestrants
Fibric acid derivatives
Niacin
These are all _______ ______ agents
lipid lowering
what percentages does niacin reduce in:
LDL
triglycerides
HDL
LDL=10-20%
triglycerides=30-70%
HDL=20-35%
niaspan is an example of ______
niacin
what should be done when taking niacin to avoid upset GI tract?
take drug WITH meals
ezetimibe, ezetimibe and simvastatin, and plant stanol ester food products are all _____ ______ agents
lipid lowering agents
which 3 agents are used for long term prevention and treatment of angina pectoris?
isosorbide dinitrate
isosorbide mononitrate
CCBs
amyl nitrate and nitroglycerin are both _____ _______ agents for angina pectoris
fast acting
what does nitroglycerin do?
VASODILATE!
isosorbide mononitrate or dinitrate are both used to prevent and treat angina caused by _____ and are NOT the first choice of drugs
CAD
T/F pt's with CAD can recieve care if 4 MET is met
true
when is the best time to schedule someone with angina pectoris?
early morning
short appts
if a patient is experiencing MI, what should be administered after contacting EMS?
provide oxygen and 325 mg aspirin
xerostomia, gingival enlargement and blood dycrasias are all ADEs of ________ agents
antiarrhythmic
an antiarrhythmic agent + ________ increases CNS effects when anesthetic is used
propafenone
t/f vasoconstrictors may interact adversely with digoxin and nonselective beta-adrenergic blocking drugs