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Common Cytogenetic Findings in Mature B-Cell Neoplasms
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Follicular
t(14;18)(q32;q21) (IGH@-BCL2)
MALT
t(11;18)(q21;q21) (API2-MALT1): lung/gastric*
t(14;18)(q32;q21) (IGH@-MALT1): ocular adnexa/salivary gland
t(3;14)(p14;q32)(IGH@-FOXP1): thyroid, ocular adnexa, skin
Trisomy 3
*Gastric MALT refractory to H.pylori eradication therapy
Splenic Marginal Zone
del(7)(q22-32)
Diffuse Large B-cell
BCL2 rearrangements [i.e. t(14;18)]
3q27 (BCL6) rearrangements
Burkitt
Translocations of 8q24 (MYC) to either 14q32 (IGH), 2q11 (IGK), 22q11 (IGL)
Mantle Cell
t(11;14)(q13;q32) (CCND1-IGH@)
Author
elzotter
ID
77295
Card Set
Common Cytogenetic Findings in Mature B-Cell Neoplasms
Description
cytogenetics, molecular, lymphoma
Updated
2011-04-04T18:45:11Z
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