Medication Used in Musculoskelatal Diseases

  1. Skeletal muscle relaxants
    Used to prevent or relieve muscle spasms. To treat spasticity(involuntary continuous muscle contraction) associated with spinal cord disease or lesions
  2. Skeletal muscle relaxants Contraindicated
    • Severe liver, renal, or heart disease
    • Should not be taken with CNS depressants
  3. Skeletal muscle relaxants Common Side effects
    • Dizziness drowsiness and hypotension
    • Dry mouth
    • Gastrointestinal (GI) upset
    • Photosensitivity
    • Liver toxicity
  4. Anti-Gout Medications
    • They inhibit production of uric acid
    • They increase uric acid excretion in kidney
  5. Anti-Gout Medications side effect
    • Blood dyscrasias such as bone marrow depression Flushed skin and skin rash
    • Uric acid kidney stones
    • Sore gums
    • Metallic taste-in the mouth
  6. Anti-Gout Medications Interventions
    • Monitor serum uric acid levels
    • Maintain a fluid intake of at least 2000 to 3000 mL/day to flush the kidney to avoid kidney stones
    • Instruct the client to avoid foods high in purine, such as wine, alcohol, organ meats, sardines, salmon, and gravy
  7. Acetylsalicylic acid (Aspirin)
    Nonsteroidal anti- inflammatory drugs (NSAIDS)
    Gold therapy
  8. Gold Therapy
    Use to treat rheumatoid arthritis
  9. Gold Therapy Side effects
    • Alopecia
    • Stomatitis, Diarrhea and Hepatitis
    • Gold toxicity
  10. Gold Therapy Interventions
    • monitor the client for 30 minutes after injec­tion for possible allergic reaction
    • Educate client about the signs and symptoms of gold toxicity, which include pruritis, skin rash, metallic taste, stomatitis, and diarrhea
  11. Dimercaprol
    Gold Therapy antitoxity
  12. Azathioprine (Imuran)
    is an immunosuppressant, that is, a drug that is used to suppress the immune system.
  13. Etartercept (Enbrel)
    Used to inhibit the inflammatory response associated with arthritis.
  14. Hydroxychloroquine sulfate (Plaquenil)
  15. Leflunomide (Arava)Causes
    hair loss
  16. Penicillamine (Cuprimine)
    chelating agent meaning it attaches to and removes certain chemicals from the body-such as uric acid, metal such as copper in Wilson diseases and iron in iron poison.
  17. Calcium and vitamin D supplementation
    Estrogen replacement therapy
    Calcitonin (Calcimar)
  18. Bisphosphonates
    These are medication used to inhibit the natural process of dissoving and removing old bone cells
  19. Bisphosphonates side effect
    Causes severe gastrointestinal side effects
  20. Bisphosphonates intervention
    Patient should not lie down or recline; patient should not eat or drink anything other than plain water; and do not take any other medicines including vitamins, calcium, or antacids
  21. Estrogen replacement Therapy
    Mimic the effect of estrogen in bone by reducing bone resorption
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Medication Used in Musculoskelatal Diseases
Musculoskelatal Medication