-
Class:
Depolarizing neuromuscular blocking agent
-
Description:
Short acting depolarizing skeletal muscle relaxant used to facilitate ET intubation
-
Mechanism of Action:
Short acting depolarizing skeletal muscle relaxant. It combines with cholinergic receptors in the motor nerves to cause depolarization, thus inhibiting neuromuscular transmission and blocks acetylcholine. Paralysis occurs in the eyelids and jaw first and the intercostal and diaphragm last. NO EFFECT ON CONSCIOUSNESS
-
Onset of Action:
- Onset: IV 30-60 seconds / IM 2-3 minutes
- Peak: 1-3 minutes
- Duration: IV 2-3 minutes / IM 10-30 minutes
- Half-Life: 5-10 minutes
-
Indications:
Achieve paralysis to facilitate ET intubation
-
Contraindications:
Known hypersensitivity to drug, penetrating eye injuries, pt with hx of narrow angle glaucoma, inexperience with use of Succinylcholine
-
Precautions:
Persons skilled in ET intubation present, emergency resuscitative drugs available, cardiac arrest & ventricular dysrhythmias have occurred in severe burn & crush patients, fractures have occurred in pediatric patients
-
Side effects:
Apnea, aspiration, bradycardia, bronchospasm, cardiac arrest, dysrhythmias, HTN, hypotension, increase intraocular pressure, intracranial pressure, prolonged paralysis, respiratory depression, wheezing
-
Adult dose:
1-1.5 mg/kg (40-100 mg in an adult)
-
-
Max dose:
One dose pre-hospital (1-1.5 mg/kg)
-
Routes of administration:
IV/IO
-
How supplied:
Not answered yet
|
|
