Vecuronium (Norcuron)

Non-depolarizing neuromuscular-blocking agent

Derivative of pancuronium, provide muscle relaxation for ET intubation

Competes with acetylcholine for cholinergic receptor sites on the post-junctional membrane. This completion results in paralysis of muscle fibers served by the occupied neuromuscular junction. Does not cause initial depolarization wave, as does succinylcholine

• Onset: <1 min
• Peak: 3-5 min
• Duration: 25-40 min
• Half Life: 30-80 min

Facilitate paralysis for endotracheal intubation

Known hypersensitivity to drug

Persons skilled in ET intubation present, Emergency resuscitative drugs available, Paralysis occurs in 1 minute and lasts 30 minutes

Apnea, aspiration, bradycardia, bronchospasm, cardiac arrest, dysrhythmias, hypotension, HTN, increased intraocular pressure, intracranial pressure, prolonged paralysis, respiratory depression, wheezing

.08-.1 mg/kg

.1 mg/kg

No answer yet....one dose I would assume?

IV/IO

No answer yet