Vecuronium (Norcuron)

  1. Class:
    Non-depolarizing neuromuscular-blocking agent
  2. Description:
    Derivative of pancuronium, provide muscle relaxation for ET intubation
  3. Mechanism of Action:
    Competes with acetylcholine for cholinergic receptor sites on the post-junctional membrane. This completion results in paralysis of muscle fibers served by the occupied neuromuscular junction. Does not cause initial depolarization wave, as does succinylcholine
  4. Onset of Action:
    • Onset: <1 min
    • Peak: 3-5 min
    • Duration: 25-40 min
    • Half Life: 30-80 min
  5. Indications:
    Facilitate paralysis for endotracheal intubation
  6. Contraindications:
    Known hypersensitivity to drug
  7. Precautions:
    Persons skilled in ET intubation present, Emergency resuscitative drugs available, Paralysis occurs in 1 minute and lasts 30 minutes
  8. Side effects:
    Apnea, aspiration, bradycardia, bronchospasm, cardiac arrest, dysrhythmias, hypotension, HTN, increased intraocular pressure, intracranial pressure, prolonged paralysis, respiratory depression, wheezing
  9. Adult dose:
    .08-.1 mg/kg
  10. Pedi dose:
    .1 mg/kg
  11. Max dose:
    No answer dose I would assume?
  12. Routes of administration:
  13. How supplied:
    No answer yet
Card Set
Vecuronium (Norcuron)
Paramedic Drugs