1. a pt with GERD would most likely experience reflux when?
    • laying flat
    • stooping after a meal
  2. what position would you want to place a pt with GERD
  3. t/f seeing a pt with GERD after a meal is best
    false-want to see before meal
  4. are there oral signs related to GERD?
    teeth may be affectd by chemical erosion
  5. describe the medical treatment of GERD. Which therapy is most effective for esophagitis?
    • neutralizing stomach contents or reducing gastric acid secretion
    • omeprazole alone or comb iwth cisapride for esophagitis
  6. what is the mechanism of action for the H2 receptor blocking agents
    • antihistamines block receptors in GI tract
    • inhibit action of histamine at receptors of parietal cells
  7. describe the strategy for reducing the drug-drug interactions when one drug affects the absorption of another
    stagger administation
  8. describe the mechanism of action of PPIs and their effects
    binds to proton pump of parietal cells and inhibts final step in secretion of hydrogen ions into gastric lumen
  9. why should enteric coated asprin be avoided if PPIs are taken
    PPIs may cause enteric coated salicylates to dissovle rapidly, increasing gastric side effects
  10. list potential drug interactions or oral effects of interactions with PPIs
    • dental drug diaxepam, fluaxepam and trazolam toxicity with omeprazole or esomeprazole
    • black tongue, glossitis and stomatitis
  11. what is the drug that prevents ulcers when NSAIDS are needed on a chronic basis?
  12. what is the principal symptom of PUD
  13. describe the medical treatemtn for PUD
    • antibacterial chemotherapy, administration of H2 receptor blocking agents and antacidds
    • agents that increase gastric emptying rate, preventative coating of the stomach, anticholinergic agents, endogenous prostaglandins
  14. what are the antacids used to treat PUD
    • magnesium hydroxide
    • aluminum hydroxide
    • calcium carbonate
    • sodium bicarbonate
  15. what is the anticholinergic drug used to treath PUD and what is the mechanism of action
    • propantheline (pro-banthine)
    • inhibits muscarinic actions of acetylcholine at prostganglionic PANS neuroeffector sites
  16. identify a risk associated with the use of calcium carbonate antacids
  17. wha tis commonly used to prepare for colonoscopy
    magnesium citrate
  18. identify agents used in the medical management of constipation
    • bulk-forming agents and saline laxatives
    • irritants(danthron, castor oil, senna, bisacodyl and phenolphthalein)
  19. identify an agent in this group that is used to prepare for colonoscopy
    magnesium citrate
  20. list irritants used to manage constipation
    • danthron
    • castor oil
    • senna
    • bisocodyl
    • phenolphthalein
  21. list agents used to manage symptoms associated with diarrhea and IBS
    • clear liquid diet and increased fluid intake
    • opiates
    • absorbents
    • hypolipoproteinemia
    • anti-inflammaotry agents
    • IBS-fibers for constipation and diphenoxylate or loperaminde for diarrhea
  22. a drug used to control nausea and emesis associated with general anesthesia
  23. identify the area of the brain that controls vomiting
  24. what are the most common agents used to reduce vomiting
    • promethazine
    • metoclopramide
  25. describe the mechanism of action of phenothiazines
    block dopamine receptors in the chemoreceptor trigger zone of medulla
  26. list a cannabinoid used in emesis management. is it a scheduled drug?
    • dronabinol (marinol)
    • controlled substance schedule III
  27. identify a drug of choice for first trimester nausea associated with pregnancy
  28. cetirizine, chlorpheniramine, loratadine and diphenhydramine
  29. list examples of agents used to prevent motion sickness
    • scopolamine (transderm-scop)
    • propantheline bromide (pro banthine)
  30. what are the ADEs associated with drugs used for urinary incontinence
    xerostomia, dry eyes, tachycardia, dyspepsia, constipation, headache, congnitve impairment and urinary retention
Card Set
ch 15 self study review questions