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Diltiazem HCL
Trade Name
Cardizem
Diltiazem HCL
Class
Calcium channel blocker
Diltiazem HCL
Mechanism of Action
Block influx of calcium ions into cardiac muscle:
Prevents spasm of coronary arteries
Arterial and venous vasodilator
Reduces preload and afterload
Reduces myocardial oxygen demand
Diltiazem HCL
Indications
Control of rapid ventricular rates
Atrial Flutter
Atrial Fibrillation
SVT
Diltiazem HCL
Contraindications
Hypotension
Sick sinus syndrome
Second or Third degree Heart Block
Cardiogenic shock
Wide-complex Tachycardias
Diltiazem HCL
Adverse Reactions
Bradycardia
Second or Third Degree Heart Blocks
Chest pain
CHF
Syncope
V-Fib
V-tach
Nausea/Vomiting
Dizziness
Dry mouth
Dyspnea
Headache
Diltiazem HCL
Drug Interactions
Caution in patients using medications that affect cardiac contractility
In general, should not be used in patients on Beta-blockers
Diltiazem HCL
How Supplied
25 mg/5 ml vial
50 mg/10 ml vial
Diltiazem HCL
Dosage and Administration
Adult
Initial bolus
: 0.25 mg/kg (average dose 20 mg) IVP over two (2) minutes.
If inadequate response, may re-bolus in 15 minutes
: 0.35 mg/kg IV over two (2) minutes.
Maintenance infusion of 5-15 mg/hour
Diltiazem HCL
Dosage and Administration
Pediatric
Not recommended
Diltiazem HCL
Duration of Action
Onset
: 2-5 minutes
Peak effect
: Variable
Duration
: 1-3 hours
Diltiazem HCL
Special Considerations
Pregnancy safety
: Category C
Use in caution in patients with renal or hepatic
dysfunction
PVCs may be noted at time of conversion of SVT
Standard EMS dose may exceed standard ED dose
ONLY GOOD FOR 30 DAYS NON-REFRIGERATED
Author
papeirce
ID
77032
Card Set
diltiazem_hcl.txt
Description
Prehospital Medication Flashcards for Paramedic School - Massachusetts and Rhode Island
Updated
2011-04-03T20:39:52Z
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