-
*H1 antagonist; blocks action of histamine at the H1 receptor site
* Have 3 properties
- Antihistaminic
- Anticholinergic
- Sedative
Antihistamines
-
-Used for the management of symptoms from nasal allergies, allergic rhinitis, motion sickness, parkinsons, sleep disorders, common cold
-Peripheral and Central acting
-(Benadryl and Clor-trimaton)
Traditional Antihistamines
-
-Controls symptoms of allergies, common cold, allergic rhinitis
-Longer duration
-Peripheral acting
-Non drowsy
-(Claritin, Allegra, Zyrtec)
Non-Sedating Antihistamines
-
-Prolonged effects
-Less potent than topical
-No rebound congestion
-(Sudafed)
Oral Decongestant
-
-Prompt onset
-Potent
-Causes rebound congestion
Topical Decongestant
-
-Takes a few weeks to kick in
-Flonase
Intranasal Steroids
-
-Constrict small blood vessles
-Mucous membranes better able to drain
-Nasal stuffiness is relieved
Nasal Decongestant
-
Nervousness/Insomnia/Palpitations/Tremors
Side effects of Adrenergics
-
-Used to stop or reduce coughing
-Used only for a NON productive cough
-Hydrocodone;Robitussin AC
Antitussives
-
-Aids in the removal of mucus by thinning it
-Drink with 8oz of fluid
-Guaifenesin (N/V, gastric irrit)
-Iodinated glycerol (GI irrit, rash, elarged thyroid gland)
-Potassim Iodide ( N/V, taste alteration)
Expectorants
-
-Used during acute asthma attacks
-Quickly reduces airway constriction and restores normal airflow
Bronchodialators (B-agonists)
-
Three types
-Non-Selective adrenergics (epinepherine;insomnia,restlessness, anorexia,tremor)
-Non-Selective B-adrenergics (alupent; cardiac stimulation, anginal pain, hypotension)
-Selective B2 adrenergics (Albuterol(Xopenex); hypotension, vascular headache,tremor)
*must take exactly as prescribed,get prompt tx for the flu,take measures to promote good health, and monitor for adverse effects
Types of Bronchodialators, there side effects, and nursing implications
-
-Used to prevent bronchoconstriction by stopping ACh from binding
-Slow and prolonged action
- Atrovent/Spiriva (dry mouth,nasal cong, heart palp, GI distress, H/A, coughing, anxiety)
Anticholinergics
-
-Plant alkaloids, caffeine, thoebromine, thoephylline
-Synthetic xanthines: aminophylline,dyphylline, oxitriphylline
-smooth muscle dilation, bronchodilation, and increased air flow
Bronchodilators (Xanthine Derivatives)
-
-Used in tx of asthma, chronic bronchitis, and emphysema
-Adjunct drug in management of COPD
-Adverse Effects; N/V, anorexia,GERD during sleep, sinus tach, palpitations
Xanthine derivatives
-
-Singulair, Zyflo
-Also called LRTAs; newer class of asthma med
-prevents leukotrienes from attatching to receptors on cells in the lungs and in circulation
Antileukotrienes
-
-Prevention and Tx of asthma in adults and children over 12
-NOT for acute asthma attacks
-Improvement seen in 1 wk
Antileukotrienes
-
-Antiinflammatory
-Used for Chronic asthma NOT attacks
-May take several wks to kick in
Corticosteroids
-
-Flovent, Flonase
-NOT first choice for acute attacks of asthma
-Must rinse mouth after to prevent oral fungal infection
-Adverse effects; dry mouth, cough, oral fungal infections
Inhaled corticosteroids
-
-Taken 0-15 min before meal
-Onset 5-15 min
-Novalog, Humalog
(pneumonic: logs travel down the rapids)
Rapid Acting Insulin
-
-Taken 30-45 min before meals
-Onset 30-60 min
-Only insulin that can be given IV Bolus, IV infus, insulin pump
-Humulin R, Novolin R
Short acting (Regular) Insulin
-
-NPH, Humulin N, Novolin N
INtermediate Acting Insulin
-
- Lantus
-Injected once a day in the AM or PM
-Steady and continuous; no peak
-CANNOT be mixed
Long acting Insulin (basal)
-
-Do not heat/freeze-avoiding sunlight exposure
-In-use Vials may be left at room temp for 4 wks (Lantus only 28 days)
-Extra should be refrigerated
Storage of insulin
-
-Fastest absorbtion from abd
-Rotate inj withine one site(like a checker board)
-Dont inject into area to be exersised
-1ml = 100 Units
Insulin Administration
-
-Continuous SC infusion for tight control of glucose inserted in abd wall
Insulin pump
-
-Exubera
-Rapid acting dry powder
-not recommended for asthma pts
Inhaled Insulin
-
-Used in Type II
-Works on Insulin resistance, decreased insulin production, increased hepatic glucose
-NOT insulin
Oral Antidiabetic (OA)
-
-Squeezes pancreas to spit out more insulin
-Used in Type II
-Cant take if allergic to sulfa
-Adverse effects; nausea, fullness, hypoglycemia, heartburn
-Allergic cross-sensitivity with loop-diuretics and sulfonamide antibiotic
-Glucotrol, Amaryl
Sulfonylureas (OA)
-
-dont take if meal is skipped
-take 30 min before meal
-Adverse effects; headache, dizziness, weight gain, joint pain, upper resp infect, flu like symptoms
-Prandin, Starlix
-Meglitinides
-
-Decreases production of glucose by liver
-Does not promote weight gain
-Stop 2 days before dye tests
-Adverse effects; diarrhea, abd bloating, cramping
-Metformin, glucophage
Biguanides
-
-"insulin sensitizing drugs"
-moderate weight gain, edema, mild anemia
-Actos, Avandia
Thiazolidinediones
-
-Should have liver function tests done
-Must take with the FIRST bite of each meal
-Adverse effects; flatulence, diarrhea, abd pain
-Precose, glyset
Alpha-glucosidase inhibitors
-
-Turns urine Orange/Red
-Used to tx or precent TB
Rifampine
-
-Mimics the incretin hormones
-Given by SC
-Cant use with insulin
-ONLY for type II
Byetta
-
Regular or Rapid acting insulin first
withdrawing two typs of insulin in one syringe
|
|