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malignant, immature lymphocytes multiply in the blood, bone marrow and lymphatic system
acute lymphocytic leukemia
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malignant, immature granulocytes called myeloblasts multiply in the bone marrow and blood stream
acute myelogenous
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protein found in blood
albumin
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ineqality in the size of red blood cells
anisocytosis
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protein made by white blood cells in response to foreign substances in the blood
antibody
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substance that prevent blood clotting
anticoagulant
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foreign agent that stimulates the production of an antibody
antigen
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test for the presence of antibodies that coat and damage erythrocytes; coombs test
antiglobulin
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withdrawal and separation of blood elements
apheresis
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failure of blood cell production due to aplasia of bone marrow cells
aplastic anemia
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removal and then reinfusion of patients own blood or blood components
autologous transfusion
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white blood cell, containg dark granules that stain white a basic dye
basophil
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orange- yellow pigment found in bile, it is released from the breakdown of hemoglobin when red blood cells die
bilirubin
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time required for blood to stop flowing from a tiny puncture wound
bleeding time
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blood cells or whole blood from a closely match donor are infused into a patient
blood transfusion
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needle aspiration of a small amount of bone marrow followed by examination under a microscope
bone marrow biopsy
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malignant but relatively mature lymphocytes, multiple in bone marrow, lymph nodes and spleen
chronic lymphocytic leukemia
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malignant, but relatively mature granulocytic leukocytes multiple in the bloodstream
chronic myelogeneous leukemia
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process of blood clotting
coagulation
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time required for venous blood to clot in a test tube
coagulation time
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disease of blood clotting
coagulopathy
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protein that stimulates the growth and proliferation of white blood cells
colony stimulating factor
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determination of the number of red and white blood cells, platelets, hemoglobin, hematocrit, and red cell indices, in a sample of blood
complete blood count
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specialization of cells from immature to mature forms
differentiation
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large blue or purplish patches on the skin
ecchymoses
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technique used to separate serum proteins by electrical charge
electrophoresis
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white blood cell whose granules stain intensely with an acidic eosin dye; elevated in allergic reaction
eosinophil
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increased in numbers of eosinophils in the blood stream
eosinophilia
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immature, developing red blood cell
erythroblast
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measurement of the speed at which erythrocytes settle or fall to the bottom of a test tube
erythrocytes sedimentation rate
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deficincy of red blood cells
erythrocytopenia
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formation of red blood cells
erythropoiesis
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substance produced by the kidney to stimulate bone marrow to produce erythrocytes
erythropoietin
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protein threads that form the basis of a blood clot
fibrin
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plasma protein that is converted to fibrin in the clotting process
fibrinogen
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major blood proteins; immunoglobulins, alpha, beta and gamma globulins are examples
globulins
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white blood cell with numerous dark staining granules; neutrophil, eosinophil, and basophil
granulocyte
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deficiency of granulocytes
granulocytopenia
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increased numbers of granulocytes in the blood
granulocytosis
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percentage of red blood cells in a given volume of blood
hematocrit
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formation of blood cells
hematopoiesis
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peripheral stem cells from a compatible donor are administered into the vein of a recipient
hematopoietic stem cell transplant
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excessive deposites of iron throughout the body
hemochromatosis
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blood protein containing iron; carries oxygen in red blood cells
hemoglobin
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total amount of hemoglobin in a smaple of blood
hemoglobin test
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disease or defect of hemoglobin production. sickle cell anemia is an example
hemoglobinopathy
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destruction or breakdown of blood; specificially red blood cells
hemolysis
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reduction in erythrocytes due to excess destruction of red blood cell
hemolytic anemia
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hereditary disease of blood clotting failure with abnormal bleeding. affected individuals are lacking a blood clotting factor
hemophilia
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stoppage of bleeding or circulation of blood
hemostasis
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anticoagulant found in blood and tissues
heparin
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pertaining to deficiency in color, decrease in hemoglobin in red blood cells
hypochromic
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response of the immune system to foreign invasion
immune system
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containing protein in the blood lgA, lgM, lgD, lgE
immunoglobulin antibody
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substance normally found in gastric juice that helps absorption of vitamin B12 into the bloodstream
intrinsic factor
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mechanical separation of white blood cells from the rest of the blood
leukapheresis
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white blood cell
leukocyte
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deficiency of white blood cells
leukocytopenia
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white blood cell with a single nucleus, capable of producing antibodies
lymphocyte
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presence of large red blood cells in the blood
macrocytosis
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large phagocytic cell migrating from the blood into tissues
macrophage
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large, giant cell with a big nucleus; platelet precursor found in the bone marrow
megakaryocyte
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increased numbers of small than normal red blood cells
microcytosis
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immature monocytes
monoblast
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white blood cell, with on large nucleus; enters tissues as macrophages
monocyte
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pertaining to a white blood cell with a single, round nucleus, monocyte or lymphocyte
mononuclear
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infectious disease marked by increased numbers of leukocytes and enlarged cervical lymph nodes
mononucleosis
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study of the shapes of cells; particularly red blood cells
morphology
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malignant tumor of bone marrow; overproduction of immunglobulins and destruction of bone tissue
multiple myeloma
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immature granulocytic whire blood cell; a cell normally only found in the bone marrow
myeloblasts
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pertaining to cells produced in the bone marrow
myelogenous
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derived from bone marrow
myeloid
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formation and development of bone marrow or cells that originate from it
myelopoiesis
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deficiency of neutrophils
neutropenia
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white blood cell with dark granules that stain with neutral dye; phagocyte formed in the bone marrow and the bodies first line of defense against disease
neutrophil
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increased numbers of neutrophils
neutrophilia
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relieving, but not curing illness
palliative
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deficiency of all blood cells
pancytopenia
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measurement of presence of plasma factors that act in a portion of the coagulation pathway
partial thromboplastin time
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lack of mature erythrocytes caused by inability to absorb vitamin B12 into the body
pernicious anemia
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small pin point hemorrhages caused by bleeding under the skin
petechiae
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cell that engulfs another cell of foreign organisms and destroys it
phagocyte
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liquid portion of blood containing proteins, water, salts, nutrients, hormones and vitamins
plasma
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removal of plasma from withdrawn blood by centrifuge
plasmapheresis
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clotting cell or thrombocytes
platelet
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number of platelets per cubic milimeter or microliter of blood
platelet count
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seperation of platelets from the rest of the blood
plateletpheresis
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variation in the shape of red blood cells
poikilocytosis
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increase in numbers of red blood cells
polycythemia vera
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pertaining to a multi- lobed nucleus
polymorphonuclear
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plasma protein converted to thrombin in the clotting process
prothombin
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test of the ability of blood to clot
prothombin time
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multiple pinpoint hemorrhages and accumulation of blood under the skin caused by deficiency of blotting cells
purapura
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number of erythrocytes per-cubic millimeter or microliter of blood
red blood cell count
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microscopic examination of a stained blood smear to determine the shape of individual red blood cells
Red blood cell morphology
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return of symptoms of disease
relapse
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disappearance of symptoms of disease
remission
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immature erythrocyte with a network of strands
reticulocyte
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antigen on red blood cells of Rh positive individuals
Rh factor
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plasma minus clotting proteins and clotting cells
serum
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hereditary conditon marked by abnormal sickle shape of erythrocytes and by hemolysis
sickle cell anemia
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deficiency of iron in the blood
sideropenia
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increase in numbers of sphere-shaped red blood cells, as in the type of anemia
spherocytosis
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unspecialized cell that gives rise to all forms of specialized cells in the body
stem cell
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inherited defect in the ability to produce hemoglobin, usually seen in the persons of mediterranean background
thalassemia
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enzyme necessary for blood clotting
thrombin
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platelet; clotting cell
thrombocyte
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deficiency of clotting cells
thrombocytopenia
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treatment with drugs to breakdown clots that may abnormally form in blood vessels
thrombolytic therapy
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condition of clot formation
thrombosis
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numberof leukocytes per cubic millimeter or microliter of blood
white blood cell count
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percentage of the total white blood cell count made up by different types of leukocytes
white blood cell differential
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