albuterol.txt

Proventil

• Sympathomimetic
• Bronchodilator

Selective Beta-2 agonist which stimulates adrenergic receptors of the sympathetic nervous system resulting in smooth muscle relaxation in the bronchial tree and peripheral vasculature

• Treatment of bronchospasm in patients with reversible obstructive airway disease (COPD/asthma).
• Prevention of exercise-induced bronchospasm.

• Known prior hypersensitivity reactions to Albuterol.
• Tachycardia dysrhythmias, especially those caused by digitalis.
• Synergistic with other sympathomimetics

• Often dose-related and include restlessness:
• Tremors
• Dizziness
• Palpitations
• Tachycardia
• Nervousness
• Peripheral vasodilatation
• Nausea
• Vomiting
• Hyperglycemia
• Increased blood pressure
• Paradoxical bronchospasm

• Tricyclic antidepressants may potentiate vasculature effects
• Beta-blockers are antagonistic
• May potentiate hypokalemia caused by diuretics

Solution for aerosolization: 0.5% (5 mg/ml)

Administer 2.5 mg. Dilute 0.5 ml of 0.5% solution for inhalation with 2.5 ml normal saline in nebulizer (6LPM) and administer over 10-15 minutes

Administer solution of 0.01 -0.03 ml (0.05 -0.15 mg/kg/ dose diluted in 2 ml of 0.9% Normal Saline. May repeat every 20 minutes three times

• Onset: 5 to 15 minutes
• Peak Effect: 30 minutes to 2 hours
• Duration: 3 to 4 hours

• Pregnancy Safety: Category C
• Antagonized by beta-blockers (e.g., Inderal,Lopressor)
• May precipitate angina pectoris and dysrhythmias
• Should only be administered by inhalation methodology in pre-hospital management