MOA

  1. Tetracycline
    H-bond to 30S subunit (Mg): interfere with communication between rRNA & tRNA
  2. Linezolid
    Prevent small and large subunit to bind (H-bond)
  3. Bacitracin
    Binds to Flipase
  4. Polymyxin B
    Binds Mg and disrupt membrane -> essential biochemicals leak out
  5. Daptomycin
    Binds to bacterial membrane Ca and depolarize
  6. MLS
    Binds to PTC and prevent peptide formation
  7. Sulfonamides
    Mimics PABA and prevent formation of folic acid
  8. Quinolones
    Inhibit Topoisomerase IV nd DNA Gyrase
Author
pdnguyen
ID
76435
Card Set
MOA
Description
MOA
Updated