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What are the stages of Syphilis?
- Primary Syphilis
- Secondary Syphilis (very dangerous)
- Latent Syphilis (sometimes gets skipped)
- Tertiary Syphilis
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Primary Syphilis: Symptoms
- Chancre forms at the site of T. pallidum entry
- Some people asymptomatic for this stage
- Lasts for 2-6 weeks
- Bacterium escapes into circulation
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Secondary Syphilis
- 1-6 mos post chancre
- T. pallidum seeded throughout body
- Fever and rash
- Sore Throat
- Lymphadenopathy
- Some people asymptomatic
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Complications from Secondary Syphilis
- hair loss
- arthritis like symptoms
- jaundice
- mental illness
- vision problems or discoloration
- loss of coordination
- aneurysm
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Latent Syphilis symptoms
- 30% of cases go latent after secondary stage
- Bacteria "hide"
- Antibodies still manufactured
- Individuals become noninfectious
- Bacteremia in immunocompromised
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Tertiary Syphilis and symptoms
slowly progressive inflammation (takes years or decades), a sequel to latency
- Symptoms:heart damage
- neurological damage
- disabling fatigue
- gummas (ulcers)
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Leptospirosis
- commonly thought of as a disease of developing countries, most strongly in tropics
- In the tropics: field workers, Children who play/work around fields, and US combat troops
- In the US, adolescents and young adults
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Symptoms of Leptospiremic phase of Leptospirosis
- sudden onset
- fever w/ chills
- headache
- body aches
- vomiting
- lasts 7 days
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Symptoms of Immune phase of Leptospirosis
- lower fever
- continued headache
- Weil's disease may develop in this phase: Kidney destruction, Liver damage, Jaundice, Anemia, and Neurological damage
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Lyme Disease: Skin stage
- Tick bite creates a lesion under the skin where hemolymph and host blood mix
- bacteria transfer into host
- bacteria move around under the skin, forming erythema migrans
- Symptoms:
- fever
- fatigue
- malaise
- general achiness
- headache
- tight neck
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Lyme disease: Blood Stage
- Bacteria move into the bloodstream and travel around the body
- Crowd into joints, cause symptoms similar to inflammatory arthritis
- Can get into nervous tissue, create problems
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Lyme Disease: Tissue stage
- Bacteria "hide" from the immune system inside mammal tissue cells where they become "quiet"
- Symptoms:
- Fatigue (fibromyalgia)
- Chronic arthritis
- Neurological damage
- Impairment of vision
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How to get rid of a tick
- "Encourage" it to leave:
- match method
- vaseline
- commercial product
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