MCB Exam 3-F

  1. All urinary/repro sites are sterile except ____ and ____ which have normal microbiota.
    • Urethra
    • Vagina
  2. Streptococoal Acute Glomerulonephritis S&S
    • Inflammation of glomeruli & nephrons
    • Hypertension & low urine output
  3. AIDS def
    Presence of opportunistic or rare infections associated w/the presence of HIV
  4. HIV attacks _______ which makes immune sys vulnerable to other infections.
    white blood cells
  5. Trtmt of AIDS
    • HAART- highly active retroviral therapy- which inhibits enzymes so virus dies (ie protease inhibitors, etc)
    • "cocktail" of many drugs
  6. RNA Reverse Transcriptase
    Can copy HIV's RNA genome into DNA, ready to be integrated into the cell's DNA genome
  7. HIV patients often get: (4)
    • TB
    • Leishmaniasis
    • Malaria
    • Pneumonia
  8. Orgs which cause PID (Pelvic Inflammatory Disease) (2)
    • Neisseria gonorrhoeae
    • Chlamydia trachomatis
  9. PID (Pelvic Inflammatory Disease)

    • Incubation: months-yrs after infection
    • S&S: inflammation, fever, abdominal pain; may result in Salpingitis
  10. Salpingitis
    Inflammation of fallopian tubes causes necrosis which can block it and cause sterility b/c egg can't go from fallopian tube to uterus
  11. Gonorrhea
    Neisseria gonorrhoeae

    • Incubation: 2-5 dys
    • VF: fimbriae, polysaccharide capsule, lipooligosaccharide (LOS) (G-)
    • S&S: men have painful urination, pus-filled dischrg; women none
  12. Syphilis S&S 3 stages:
    • Primary: chancre (painless, hard lesion) at site of infection
    • Secondary: widespread rash, sore throat, fever, malaise
    • Tertiary: systemic; may include dementia, blindness, paralysis, heart failure
  13. Congenital syphilis can result in:
    Death, retardation, malformation of organs
  14. Chlamydia
    Chlamydia trachomatis

    ____ pathogen
    Abt it in general:
    • Intracellular pathogen
    • Most common STD in US; Increased risk for cervical cancer
    • S&S: men have painful urination & pus dischrg; females none; lymphogranuloma venereum (severe form w/genital lesion & bubo in groin)
  15. Chlamydia trachomatis exists as 2 forms:
    • Elementary bodies- infective form (transmission from person-person)
    • Reticulate bodies- reproductive form
  16. Chancroid

    What org & who gets it:
    • Haemophilus ducreyi
    • Susceptibility: uncircumcised men
    • VF: toxin that kills epithelial cells
    • S&S: soft chancres (ulcers); women painful urination; buboes in some
Card Set
MCB Exam 3-F
Microbial Diseases of Urinary & Reproductive Systems