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All urinary/repro sites are sterile except ____ and ____ which have normal microbiota.
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Streptococoal Acute Glomerulonephritis S&S
- Inflammation of glomeruli & nephrons
- Hypertension & low urine output
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AIDS def
Presence of opportunistic or rare infections associated w/the presence of HIV
-
HIV attacks _______ which makes immune sys vulnerable to other infections.
white blood cells
-
Trtmt of AIDS
- HAART- highly active retroviral therapy- which inhibits enzymes so virus dies (ie protease inhibitors, etc)
- "cocktail" of many drugs
-
RNA Reverse Transcriptase
Can copy HIV's RNA genome into DNA, ready to be integrated into the cell's DNA genome
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HIV patients often get: (4)
- TB
- Leishmaniasis
- Malaria
- Pneumonia
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Orgs which cause PID (Pelvic Inflammatory Disease) (2)
- Neisseria gonorrhoeae
- Chlamydia trachomatis
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PID (Pelvic Inflammatory Disease)
Incubation:
S&S:
- Incubation: months-yrs after infection
- S&S: inflammation, fever, abdominal pain; may result in Salpingitis
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Salpingitis
Inflammation of fallopian tubes causes necrosis which can block it and cause sterility b/c egg can't go from fallopian tube to uterus
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Gonorrhea
Neisseria gonorrhoeae
Incubation:
VF:
S&S:
- Incubation: 2-5 dys
- VF: fimbriae, polysaccharide capsule, lipooligosaccharide (LOS) (G-)
- S&S: men have painful urination, pus-filled dischrg; women none
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Syphilis S&S 3 stages:
- Primary: chancre (painless, hard lesion) at site of infection
- Secondary: widespread rash, sore throat, fever, malaise
- Tertiary: systemic; may include dementia, blindness, paralysis, heart failure
-
Congenital syphilis can result in:
Death, retardation, malformation of organs
-
Chlamydia
Chlamydia trachomatis
____ pathogen
Abt it in general:
S&S:
- Intracellular pathogen
- Most common STD in US; Increased risk for cervical cancer
- S&S: men have painful urination & pus dischrg; females none; lymphogranuloma venereum (severe form w/genital lesion & bubo in groin)
-
Chlamydia trachomatis exists as 2 forms:
- Elementary bodies- infective form (transmission from person-person)
- Reticulate bodies- reproductive form
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Chancroid
What org & who gets it:
VF:
S&S:
- Haemophilus ducreyi
Susceptibility: uncircumcised men - VF: toxin that kills epithelial cells
- S&S: soft chancres (ulcers); women painful urination; buboes in some
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