________ more likely to be abused (e.g. Cocaine and Nicotine)
Short half life/short action drugs
Explain Pharmacodynamics
Through synapse, many drugs act by mimicking normal neurotransmitters
occupying receptor sites and sending “false” messages
Define Drug dependence, drug tolerance, drug withdrawal and cross-dependence
Drug dependence: After period of continual use can become dependant on a drug. Social, psychological and physical dependence
Drug tolerance: When dependant, less affected by drug/need more to feel effects
Drug withdrawal: When physically dependant, cessation results in withdrawal. In general withdrawal symptoms have opposite effect of the drug
Cross-dependence: One substance can take the place of another to continue physical dependence and avoid withdrawal
Depressants
Slow down brain and body
May cause initial high/euphoria
Small doses: relaxation/drowsiness
Large doses: can cause loss of consciousness, respiratory inhibition, and even death
Some appear to cause emotional depression
Impaired coordination
E.g. alcohol, heroin, cannabis, benzodiazepines and Volatile (sniffable) substances
What is the active ingredient in Canibus, and what does it do?
THC is the main active ingredient
Binds to cannabinoid receptors
Interferes with normal functioning of brain
Cerebellum: Affects coordination
Hippocampus: Affects memory
Cerebral cortex: Affects thinking
Opiates
Opiate receptors – pleasure or pain relief: Endorphins
Affects dopamine
Pain relief – Physical and Psychological Overdose risk high
Common effects
Feelings of well-being or euphoria
Pinpoint pupils
Sedation
Shallow breathing
Nausea and vomiting
Stimulates
Increase the body’s state of arousal
Accelerate central nervous system
Small doses: increase awareness and concentration, decrease fatigue and amplify positive moods
Larger doses: can cause excessive activity, irritability, nervousness, insomnia, delusions and hallucinations (drug-induced psychosis), convulsions, death
Hallucenagens
Distort the brain’s perception of reality
Can cause auditory, tactile, or visual hallucinations
Include varying degrees of depression or stimulation depending on the substance
True or False: You only need to use heroin once to become addicted
False
True or False: For dependant drinkers, withdrawal from alcohol can be fatal
True
After having a break, it’s safe to go back to using a drug at the same level
False
Is smoking in Australia decreasing?
Yes
Who smokes the most?
Men are more likely to be daily smokers and smoke more cigarettes per week (102 vs 91)
females were more likely to have ‘never smoked’ (51% vs 60%)
People aged 20-29 more likely to be daily smokers – 21% (approximately the same for 30-39 and 40-49)
l60+ age group – 9%
However, 50-59 age group smoke most cigarettes per week (125)
What are the two main reasons for people quiting smoking?
Affecting health and fitness
Costing too much
Is the prevalence rate of illicit drug use increasing?
No, over the period from 2004-2007 recent illicit drug use dropped significantly, especially among 14-19 and 30-39 age groups