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Mechanism of Action
adsorbs toxins by chemical binding and prevents gastrointestinal adsorption
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Indications
Poisoning following emesis or when emesis is contraindicated
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Contraindications
oral administration to comatose pt., after ingestion of corrosives, caustics, or petroleum distillates (ineffective and may induce vomiting); simultaneous administration with other oral drugs
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Adverse reactions
Nausea and vomiting, constipation
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Drug interactions
bonds with and generally inactivates whatever it is mixed with, eg, syrup of ipecac
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How supplied
25g (black powder)/125mL bottle (200 mg/mL); 50g (black powder)/250mL bottle (200mg/mL)
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Dosage and Administration
- Note: if not in premixed slurry, dilute with 1 part charcoal/4 parts water.
- Adult: 1-2 g/kg PO of via NGT.
- Pediatric: 1-2 g/kg PO or via NGT
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Duration of action
Depends in gastrointestinal function; will act until ecxcreted.
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Special Considerations
often used in cponjunction with magnesium citrate. Must be stored in a closed container. Does not adsorb cyanide, lithium, iron, lead, or arsenic.
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