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substance secreted by and endocrine gland and transported into the blood
hormones
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cell with specific receptors on which a hormones exerts its effect
target cell
-
type of endocrine secretion in which the hormone affects nearby cells
paracrine
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hormone that acts on the same cell that secreted it
autocrine
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gland that secretes its products into a duct or onto a body surface
exocrine gland
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(lipids) type of organic molecule including complex rings of carbon and hydrogen atoms;
all are derived from cholesterol;
includes sex hormones such as testosterone and the estrogens, and secretions of the adrenal cortex, aldosterone and cortisol
Steroid Hormones
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hormones called amines;
derived from the amino acid tyrosine;
synthesized in the adrenal medulla (inner portion of the adrenal gland);
include: protien hormones, peptide hormones, prostglandins
Nonsteroid Hormones
-
a steroid hormone;
action: stimulate the kidneys to retain sodium
aldosterone
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a second messenger
cAMP (cyclic adenosine monophosphate)
-
organic compound that activates an enzyme bound to the inner surface of a cell membrane, eliciting a signal
G Protien
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enzyme activate when certian hormones bind receptors on cell membranes;
it catalyzes the circularization of ATP to cyclic AMP/cAMP
adenylate cyclase
-
enzyme that catalyzes the reaction to form a phosphoprotein
protien kinases
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a mechanisim that restores a biochemical or other balance in which build up of a product supresses its synthesis
negative feedback
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a hormone that has an endocrine gland as its target tissue
tropic hormones
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endocrine gland attached to the base of the brain that consists of anterior and posterior lobes;
the hypophysis
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pituitary gland
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hormone released by the anterior lobe of the pituitary gland that promotes the growth of the organism
growth hormone
-
protein that promotes milk production
prolactin
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glycoprotein that controls certain hormones from the thyroid gland;
can also stimulate growth of the thyroid gland;
abnormally high levels lead to goiter
Thyroid stimulating hormone (aka - thyrotropin)
-
peptide that controls the manufacture and secretion of certain hormones from the outer layer (cortex) of the adrenal gland
adrenocorticotropic hormone
-
glycoprotein;
substance secreted by the anterior pituitary gland to stimulate development of an ovarian follicle in a femal or production of sperm cells in a male
p 497
follicle stimulating hormone (FSH)
-
a hormone that the anterior pituitary secretes that controls formation of the corpus luteum in females and testosterone secretion in males
luteinizing hormone
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hormone of the posterior pituitary gland that enhances water conservation in the kidneys; ADH, vasopressin
antidiuretic hormone
-
hormone released by the posterior lobe of the pituitary gland that contracts smooth muscles in the uterus and mammary glands
oxytocin
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endocrine gland just below the larnyx and in front of the trachea that secretes thyroid hormones
thyroid gland
-
narrow connection between two larger parts.
isthmus
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two important thyroid hormones that affect cellular metabolic rates
thyroxine and triiodothyronine
-
hormone secreted by the thyroid gland (T4)
thyroxine
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hormone secreted by the thyroid gland (T3); five times more potent that T4
triiodothyronine
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thyroid hormone that regulates blood calcium concentration; helps lower concentrations of calcium and phosphate ions by decreasing the rate at chich they leave the bones and enter extracellular fluids by inhibiting bone destruction by osteoclasts; increases excretion by kidneys.
calcitonin
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hyperthyroidism and graves disease are caused by:
hyperthyroid
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hashimoto diesase (antibodies against self attck thyroid cells resulting in hypothyroidism); hypothyroidism, and simple goiter are caused by:
hypothydroid
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symptoms: stunted growth, abnormal bone formation, mental retardation, low body temperature, sluggishness
cretinism (infantile - hypothyroidism)
-
symptoms: low metabolic rate, sensitivity to cold, sluggishness, poor appetite, swollen tissues, mental dullness
myxedema (adult - hypothyroidism)
-
symptoms: autoantibodies (against self) bind TSH receptors on thyroid cell membranes, mimicking action of TSH, overstimulating gland (hyperthyroidism); exopthalmia (protusion of the eyes) and goiter
graves disease
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symptoms: high metabolic rate, sensitivity to heat, restlessness, hyperactivity, weight loss, protruding eyes, goiter
hyperthyroidism
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one of four small endocrine glands embedded in the posterior part of the thyroid gland.
parathryoid gland
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hormone secreted by the parathyroid glands that helps regulate the level of blood calcium and phosphate ions
parathyroid hormone PTH
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endocrine gland on the superior portion of each kidney
adrenal gland
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inner part of the adrenal gland
adrenal medulla
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outer part of the adrenal gland
adrenal cortex
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epinephrine and norpinephrine are hormones of the
adrenal medulla
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hormone the adrenal medulla secretes during times of stress
epinephrine
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neurotransmitter released from the axons of some nerve fibers
norpinphrine
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produces aldosterone, cortisol, and sex hormones
adrenal cortex
-
adrenal cortical hormone that regulates sodium and potassium ion concentrations and fluid volume
aldosterone
- glucocorticoid secreted by the adrenal cortex; inhibits synthesis of protein in tissues increasing blood concentration of amino acids, promotes the release of fatty acids from lipids to use as energy, and stimulates liver cells to synthesize glucose increasing blood glucose concentrations
- cortisol
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supplement sex hormones from the gonads; may be converted into estrogens
adrenal androgens
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glandular organ in the abdominal cavitiy that secretes hormones and digestive enzymes
pancreas
-
hormone secreted by the pancreatic islets that releases glucose from glycogen
glucagon
-
hormone the pancreatic islets secrete that stimulates cells to take up glucose
insulin
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hormone secreted by the pancreatic islets that inhibits the release of growth hormone
somatostatin
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hormone that the pineal gland secretes
melatonin
-
pattern ofrepeated activity associated with the cycles of night and day
circadian rhythm
-
glandular organ in the mediastinum, behind the sternum and between the lungs
thymus
-
group of peptides the thymus gland secretes that increases production of certian types of white blood cells
thymosins
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response to factors perceived as life threatening
stress
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factor that can stimulate a stress response
stressor
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