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Description:
Naturally occurring catecholamine. Potent Alpha and Beta adrenergic stimulant. Effects on Beta receptors is more profound
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Mechanism of Action
- Increases all of the follows: HR, automaticity, cardiac contractile force, myocardial electrical activity, systemic vascular resistance, BP.
- Bronchodilation
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Onset of Action
- Onset: <2 minutes (IV/ET)
- Peak: <5 minutes (IV/ET)
- Duration: 5-10 minutes (IV/ET)
- Half-Life: 5 minutes
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Indications:
Cardiac arrest, anaphylactic shock, serve reactive airway disease, Bronchial asthma, exacerbation of COPD, allergic reactions
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Contraindications:
- Epi 1:10,000 is for IV/ET use for pt requiring extensive resuscitative efforts
- Epi 1:1,000- Underlying cardiovascular disease, HTN, pregnancy, tachydysrhythmias
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Precautions
- Should be protected from light
- Epi 1:10,000- Can be deactivated with alkaline solutions
- Epi 1:1,000- Monitor HR, BP, ECG
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Side Effects
- Anxiety,
- Headache
- Nausea and Vomiting
- Palpitations
- Taacycardia
- Tremulousness
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Adult Dose:
- Cardiac Arrest- 1mg/10ml IVP of Epi 1:10,000
- Allergic Reaction- .3mg IM/SQ Epi 1:1,000
- Anaphylaxis- 1mg/10ml IVP of Epi 1:10,000
- Wheezing secondary to Asthma- .3mg SQ of Epi 1:1,000
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Pedi-Dose:
.01 mg/kg up to .3mg
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Max Dose:
There is no max does for cardiac arrest
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Routes of Administration
IV/IO ET IM/SQ
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How Supplied
- 1:1,000: 1mg/ml
- 1:10,000: 1mg/10ml
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