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Description:
Naturally occurring catecholamine, Chemical precursor or norepinephrine. It acts on alpha, Beta one, and dopaminergic receptors. Alpha Receptors are dose dependent
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Mechanism of Action
Increase cardiac contractility, Causes peripheral vasoconstriction
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Onset of Action:
- Onset: <5 minutes
- Peak: 5-8 minutes
- Duration: < 10minutes
- Half-Life: 2 minutes
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Indications:
Hemodynamically significant hypotension not resulting from hypovolemia, cardiogenic shock
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Contraindications:
Hypovolemic shock in which complete fluid resuscitation has not occurred, Pheochromocytoma
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Precautions
Presence of severe tachydysrhythmias, presence of ventricular fibrillation, Ventricular irritability, Beneficial effects lost when dose exceeds 20ug/kg/min
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Side Effects
- Hypertension,
- Palpitations
- Ventricular Tachydysrythmias
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Adult Dose
- Renal Failure: 2-4ug/kg/min
- Cardiac: 2-10ug/kg/min
- Vasoconstriction (Alpha 1 Stimulant): 10-20 ug/kg/min
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Routes of Administration
IV drip only
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How Supplied:
400 mg Vials, 800 mg Vials, Prefilled bags
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