-
Class:
Calcium Channel Blocker
-
Description:
Calcium channel blocker that causes relaxation of vascular smooth muscle and slows conduction through AV node
-
Mechanism of Action
Slows conduction through the atrioventricular mode, causes vasodilation, decreases rate of ventricular response, decreases myocardial oxygen demand
-
Onset of Action
- Onset: 3 minutes
- Peak: 7 minutes
- Duration: 1-3 hours Half-Life: 2 hours
-
Indications:
Control rapid ventricular rates associated with A-Fib and A-Flutter, Angina pectoris, PSVT refractory to adenosine
-
Contraindications:
Hypotension, Wide complex tachycardia, conduction system disturbances, cardiogenic shock, Wolff-Parkinson-White Syndrome
-
Precautions
Not used in pts receiving IV beta blockers, hypotension, must be kept refrigerated, 30 day self-life if not refrigerated
-
Side Effects
- Asystole
- Bradycardia
- Dizziness
- Headache
- Heart block
- Hypotension
- Nausea/vomiting
-
Adult Dose
- .25mg/kg bolus (typically 20mg) IV over 2 minutes, followed by maintenance infusion of 5-15mg/hr
- PSVT: .25mg/kg IV Bolus over 2 minutes
-
-
Max Dose:
One dose in pre-hospital arena Max 25 mg
-
Routes of Administration
IV/ IO IV Drip
-
How Supplied:
Prefilled syringes and vials containing 25mg Total
|
|
