ASPIRIN

• Platelet aggregator inhibitor
• Anti-inflammatory agent

Aspirin is an anti-inflammatory agent and an inhibitor of platelet function. This makes it a useful agent in the treatment of various thromboembolic diseases such as acute MI.

Block the formation of the substance thromboxane A2, which causes platelets to aggregate and arteries to constrict. These results in an overall reduction in mortality associated with an MI

• Onset: 5-30 Minutes
• Peak Effects: 15-120 Minutes
• Duration: 1-4 Hours
• Half-life: 15-20 Minutes

New chest pain suggestive of acute coronary syndrome

• Known hypersensitivity to drug
• Acute Ulcer Disease
• Asthma

• GI upset and bleeding (Use Enteric Coated Aspirin with pts that have tendency with GI bleeding and irritation)
• Pt who report NSAID allergy
• Higher doses can interfere with possible benefits

• Heartburn
• GI bleeding
• Nausea
• Vomiting
• Wheezing
• Prolonged Bleeding

81mg tablets x 4 tablets= 324mg

Reye’s Syndrome is why ASA is not given to pedi

324mg

PO

81 mg chewable tablets