-
Signs of Hemolytic Transfusion Reaction
- Increased HR, RR
- Decreased BP
- Apprehension and doom
- Chest pain, headache, lower back pain
- DIC, hemoglobinuria
-
Signs of TRALI
- Sudden onset of respiratory distress
- Pulmonary edema
- Hypoxemia
- Absence of JVD and HTN
-
Signs of Allergic Transfusion Reaction
- Uticaria
- Itching
- Bronchospasm
- Anaphylaxis
-
Signs of Febrile Transfusion Reaction
- Fever
- Flushing
- Headache
- Muscle Pain
- Tachypnea
-
Signs of Bacterial Transfusion Reaction
- Tachycardia
- Hypotension
- Fever/chills
- Shock
- Vomiting/Diarrhea
-
Signs of Circulatory Overload
- Dyspnea
- HTN
- JVD
- Bounding Pulse
- Confusion/Restlessness
- Crackles
-
Treatment for Hemolytic Reaction
- Stop transfusion
- Manage symptoms
-
Treatment for TRALI
- Stop transfusion
- Give diuretics, antihistamines and corticosteroids
- Give Oxygen, possibly intubate
-
Treatment for Allergic Transfusion Reaction
- Stop transfusion
- Administer antihistamines, corticosteroids, epinephrine and antipyretic
-
Treatment for Febrile Transfusion Reaction
- Stop transfusion
- Administer antipyretic
-
Treatment for Bacterial Transfusion Reaction
- Stop transfusion
- Give IV fluids and supportive care
- C&S from donor and patient
- Administer broad spectrum antibiotic
-
Treatment for Circulatory Overload
- Stop Transfusion
- Administer diuretic
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