Nitroglycerine (Nitrostat)

  1. Class:
    Antianginal (Nitrate)
  2. Description:
    Potent smooth muscle relaxant
  3. Mechanism of Action:
    Smooth muscle relaxant, reduces cardiac work, dilates coronary arties, dilates systemic arteries
  4. Onset of Action:
    • Onset: 1-3 minutes
    • Peak: 5-10 minutes
    • Duration: 20-30 minutes
    • Half-Life: 1-4 minutes
  5. Indications:
    Angina, chest pain associated with myocardial infarction, pulmonary edema
  6. Contraindications:
    Hypotension, Children under 12, Recent use of male enhancement medication
  7. Precautions:
    Monitor BP, Syncope, Protected from light, expires quickly once bottle is open
  8. Side effects:
    Dizziness, headache, hypotension
  9. Adult dose:
    • Tablet: One .4mg tablet every 3-5 mins intervals up to 3 tablets
    • Spray: One .4mg spray every 3-5 minutes up to 3 sprays
    • Paste: 0.5 to 1 inch (use only if SL nitro has proven to be working)
  10. Pedi dose
    Not indicated
  11. Max dose:
    3 Tablets, 3 Sprays, 1 Inch
  12. Routes of administration:
    Sub lingual, trans dermal
  13. How supplied:
    Tablets, spray, paste
Card Set
Nitroglycerine (Nitrostat)
Paramedic drugs