Virology Flaviviridae

Flaviviridae's virion is ___________.

Icosahedral and enveloped
Flaviviridae's envelope is characterised by ____________.

Glycoproteins with icosahedral symmetry
Flaviviridae's genome is _________.

Linear (+) ssRNA
Flaviviridae's genome features _______.

a 5' cap an no poly A tail.
Flaviviridae's genes are translated ___________ and ____________.

as 1 polyprotein that is that is processed by viral and cellular proteinases
NS2/3 is_________ to create ______ which is a ______.

A nonstructural autoprotease that cleaves at the NS2/3 junction to make NS3/4 which is a bifunctional protein for polyprotein processing and RNA rep
Diseases caused by Flavi include _______...
- Yellow fever
- Dengue Fever
- Hepatitis C
Flaviviridae's distinct characteristics include ______, ________, __________, ________.
- Vector transmission (not hep C)
- Major envelope protein (E1/2) is parallel to lipid membrane
- Pesti and Hepaci have IRES
- Virions assemble by budding at the ER and are released by exocytosis

Author

p.reilly1227

75004

Card Set

Virology Flaviviridae

Description

Virology Flaviviridae

Updated

2011-03-24T19:13:34Z

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