Picornaviridae

Picornaviridae's virion is ___________.

naked icosahedron
Picornaviridae's genome is ___________.

Linear (+) ssRNA
Picornaviridae's genome features _____________.

5' NTR with IRES, VPg, and a poly A tail
Picornaviridae's genes are translated___________.

Ttranslated as 1 polyprotein that is autocatalytically cleaved by viral proteinases.
Autocatalytic cleavage works by _________, which is why________?

As picornaviridae's genome is translated, the secondary structure folds and forms a proteinase while still part of the polyprotein. This section of the protein cleaves itself and acts as a proteinase for other regions which frees up other proteinases and individual proteins. For this reason a complete full-length polyproteins are rarely found.
Examples of diseases caused by Picornaviridae include ________.
- Rhino
- Poilio
- Meningitis
- Hepatitis A
- Myocarditis
Picornaviridae's distinct characteristics include _______, __________, ___________.
- Translation begins at IRES
- Autoproteolytic cleavage
- RNA replication is associated with vesicles in the cytoplasm.

Author

p.reilly1227

75001

Card Set

Picornaviridae

Description

Virology, Picornaviridae

Updated

2011-03-24T19:17:03Z

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