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Virion Shape, Size, Envelope?
- Complex
- 300X250X150
- 2 envelopes (IMV, EEV)
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Pox genome type?
Closed, linear, dsDNA
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Special genome characteristic and why it is present?
10 kb terminal repeat. Created during rolling hairpin replication - where concatemers are cut, same place everytime.
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Pox genes all have ________ and _________.
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Pox proteins are called ________________.
Early, Intermediate, Late
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Pox early genes are responsible for ____________.
Dissolving core, directing DNA rep, and intermediate gene expression.
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Pox intermediate genes are responsible for _________.
Regulating late gene expression
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Pox late genes are responsible for _____________.
Structural proteins, RNA pol, and RNA processing.
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Examples of Pox.
Small Pox
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Special characteristics of pox are ______, _________, ________, ________.
- Virus coded enzymes for transcription and RNA processing (late proteins) are packaged in core.
- Early RNA is made in the core
- DNA replicates in the cytoplasm using only viral proteins
- Internal envelope is assembles de novo
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