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cellular respiration
chemical process that uses oxygen to convert the chemical energy stored in fuel molecules to a form of chemical energy that the cell can use to perform work
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ENDERgonic reactions
"energy inward"
yield products that are rich in potential energy
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metabolism
- the total of an organisms chemical reactions.
- intersecting metabolic pathways.
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metabolic pathway
a series of chemical reactions that either builds a complex molecule or breaks down a complex molecule into simpler compounds
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energy coupling
- the use of energy released from EXERgonic reactions to drive essential ENDERgonic reactions
- a crucial ability of all cells
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ATP
powers nearly all forms of cellular work
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phosphorylation
- the transfer of a phosphate group, usually from ATP, to a molecule.
- *nearly all cellular work depends on ATP energizing other molecules by phosphorylation
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Energy Activation (EA)
the amount of energy that reactants must absorb before a chemical reaction will start
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enzymes
proteins that function as biological catalysts, increasing the rate of a reaction without being consumed by the reaction
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substrate
a specific reactant that an enzyme acts on
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active site
the region of an enzyme that the substrate fits into
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induced fit
the change in shape of the active enzyme, induced my entry of the substrate do that it binds more snuggly to the substrate
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competitive inhibitor
- reduces an enzyme's productivety by blocking substrates from entering the active site
- can be overcome by increasing the concentration of substrate
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fluid mosaic
a description of a membrane structure, depicting a cellular membrane as a mosaic of diverse protein molecules embedded in a fluid bilayer made of phospholipid molecules
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selective permeability
allow some substances to cross more easily than others
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concentration gradient
- an increase/decrease in the density of a chemical substance in an area.
- cells often maintain concentration gradients of ions across their membranes
- when a gradient exists, substances tend to move from where they are more concentrated to where they are less concentrated
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passive transport
the diffusion of a substance across a biological membrane, without any input of energy
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tonicity
the ability of a solution surrounding the cell to cause that cell to gain or lose water
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isotonic solution
has the same solute concentration as another solution, thus having no effect on passage of water into or out of the cell
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hypotonic solution
- a solution with a concentration lower than that of the cell
- the cell gains water, swells, and may burst
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hypertonic solution
- a solution with a higher solute concentration
- the cell shrivels and can die from water loss
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facilitated solution
the passage of a substance through a specific transport protein across a biological membrane down its concentration gradient
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aquaporins
a transport protein that very rapidly diffuses water into and out of cells
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active transport
a cell must expend energy to move a solute against its concentration gradient-that is, across a membrane toward the side where the solute is more concentrated. the energy molecule ATP supplies most of the energy
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EXocytosis
the movement of materials out of the cytoplasm of a cell by fusion of vesicles with the plasma membrane
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ENDocytosis
cellular uptake of molecules or particles via formation of new vesicles from the plasma membrane
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PHAGocytosis
cellular "eating"; a type of ENDocytosis where a cell engulfs macromolecules, other cells, or particles into its cytoplasm
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pinocytosis
cellular "drinking"; a type of ENDocytosis in which the cell makes fluid and dissolved solutes into small membrane vesicles
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receptor-mediated endocytosis
- the movements of specific molecules into a cell by the inward budding of membrane vesicles
- the vesicles contain protein with receptor sites specific to the molecules taken in
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noncompetitive inhibitor
- does not enter the active site, but instead binds to the enzyme somewhere else
- its binding changes the shape of the enzyme so that the active site no longer fits the substrate
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feedback inhibition
a method of metabolic control in which a product of a metabolic pathway acts as an inhibitor of an enzyme within that pathway
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energy
the capacity to perform work
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kinetic energy
- the energy of motion
- transferring motion to other matter
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potential energy
stored energy that an object possesses as a result of its location or structure
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chemical energy
the potential energy available for release in a chemical reaction
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thermodynamics
the study of energy transformation that occurs in a collection of matter
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First law of thermodynamics
- the principle of the conservation of energy
- energy can be transferred and transformed, but cannot be created or destroyed
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entropy
- a measure of disorder or randomness
- the more randomly arranged a collection of matter it, the greater its entropy
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Second law of thermodynamics
- the principle whereby every energy conversion reduces the order of the universe, increasing its entropy
- ordered forms of entropy are at least partly converted to heat
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EXERgonic reaction
a chemical reaction that releases energy
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