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How are Science and Technology different from each other?
Science: used to "Understand Nature"
Technology: used to "Apply Knowledge"
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How do Science and Technology "depend" on each other?
- Science is used to make DISCOVERIES
- Technology is used to make INVENTIONS
*More discoveries equal greater inventions, we discover stuff through inventions
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What drives science?
Curiosity
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What drives Technology?
Wants and Needs
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What compounds are "organic molecules?"
- Compounds that contain hydrogen-carbon bonds.
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Hydrophillic Macromolecule Property
"Water loving" (Dissolves in water)
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Hydrophobic Macromolecule Property
"Water fearing" (Does NOT dissolve in water)
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Macromolecules properties depend on:
Size and Shape
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Macromolecules (Definition and explanation of structure)
Def: Large Organic Compounds/Molecules
- Structure:
- Creation- remove water + dehydration
- Breaking- Add water (Hydrolysis)
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Classes of Macromolecules
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Types of Carbohydrates (Sugars)
- "Hydrophillic"
- 1. Monosaccharide - one sugar
- 2. Polysaccharide- more than one sugar unit together
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Protein Polymer (def)
Long chain of Amino Acids (AA-AA-AA-AA)
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Protein Functions
- Enzymes
- Transporters
- Signals (Hormones)
- Defense (Antibodies)
- Storage
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Protein Shapes
- (They build on each other)
- 1. Primary level: Amino Acid Chain (polypeptide)
- 2. Secondary Level: Polypeptide chain becomes "telephone wire" (alphahelix) or "mountains" (Beta sheets)
- 3. Tertiary Level: combination of alphahelix and beta sheets
- 4. Quartnery level: combining tertiary shapes together 88
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Unsaturated Lipids Qualities
- "Kinks" in structure (not tightly packed)
- Liquid at room temp
- Healthy Fats (Veggie oil, Canola Oil, Olive Oil)
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Saturated Fats Qualities
- "No Kinks" in structure (tightly packed)
- Solid at room temp
- Unhealthy (eggs, ice cream, steaks, butter)
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What is a Nucleic Acid?
A Polymer of Nucleotides
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Nucleotide Diagram with 3 components
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2 Types of Nucleic Acid
- DNA (Deoxyribonucleic Acid)
- RNA (Ribonucleic Acid)
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DNA Qualities and 4 Bases
- Shown as "2 strands"
- Nitrogenous
- 4 Bases:
- 1. Adenine
- 2. Guanine
- 3. Cytosine
*4. Thymine (different from RNA)
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RNA Qualities and 4 Bases
- Shown as "1 strand"
- Nitrogenous
- 4 Bases:
- 1. Adenine
- 2.Guanine
- 3. Cytosine
*4. Uracil (Different from DNA)
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Inductive Reasoning
- Form of Discovery Science
- "Specific to General" (Specific observations to general conclusions)
- Ex. an individual with black and white strips is a zebra---All zebras have black and white stripes
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Deductive Reasoning
- Form of Hypothesis Science
- "General to Specific"
- Hypothesis --> Experiment
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Limitations of Science
- "Anything that cannot be tested, proved, disproved"
- A.God
- B. Proving supernatural
- C. Faith or Belief
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Biology (meaning)
"The study of life"
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Cell (meaning and description)
- "Fundamental unit of life"
- 1. Enclosed in membraine with passage
- 2. DNA- genetic information
- 3. Two types:
- -Prokaryotic- simple (very diverse, bacteria)
- -Eukaryotic- complex (plants, people, mushrooms)
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Hypothesis Science Format/Steps
- 1. Observation (usually from discovery science) leads to wanting an explanation
- 2. Hypothesis (Proposed explanation) must be testable and falsifiable.
- 3. Experiment/Test:
- Control group- no change; used to compare
- Experimental group- change of simple variable
- Conclusion- test falsifies or does not falsify hypothesis
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Hypothesis must meet 2 conditions:
Testable and Falsifiable
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Theory (explanation)
- Broad in scope
- -explains several observations
- -supported by large amounts of evidence
- -generates new hypothesis
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2 general groups of Microscopes
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Discovery Science
- "Describes" nature
- Uses Inductive Reasoning
- based on Observations and measurements
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Hypothesis Science
- "Explains" Nature
- Uses Deductive Reasoning
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Homeostasis (explanation)
- Regulation of internal environment (PH and temp)
- Ex. "Sweating in human beings)
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What Macromolecule are Enzymes?
Protein
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What 3 Letters Do ALL Enzymes End In?
ASE
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What Do Enzymes Do?
- Function is to speed up (Catalyze) reaction.
- control how fast "reactants" become "products"
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All Enzyme reactions begin with__ and end with __?
Reactants, Product
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Enzyme Substrate
A molecule upon which an enzyme acts
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Where do substrated bind to enzymes?
Active site
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Enzymes at Cellular Level are "Substrate Specific" what does that mean?
Enzymes are specific to substrates, if they can't fit, they will not go into enzyme
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What is Denaturation?
When Enzyme breaks down losing shape and function due to temp. too high or PH incorrect
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What is an Enzyme Inhibitor?
Chemical that interferes with enzyme activity
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2 types of Enzyme Inhibitors
- Competitve
- Non-Competitive
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Competitive Inhibitor
- Resembles substrate and competes for active site
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Non-Competitive Inhibitor
- Bind to enzyme but they bind at a different site, not active site.
- This changes active site and renders it useless
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Feedback Inhibition
- Quantity of Products are too high
- Result: Product becomes non-competitive inhibitor
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Examples of Inhibitors
- Poisons and chemical warfare
- Pesticides
- Penecillin (inhibits bacteria)
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What does Prokaryotic mean?
"Before Nucleus" has NO NUCLEUS!
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What does Eukaryotic mean?
"True Nucleus" HAS NUCLEUS!
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4 Common Things That All Cells Share
- DNA (Genetic info)
- Membrane- used as protection from environment
- Ribosomes-Structures that produce protein
- Cytoplasm- Fluid that internal structures suspend in
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What is the function of Ribosomes?
Produce protein
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Organism composed of Prokaryotic Cells
Bacteria
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Organsims composed of Eukaryotic Cells
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Prokaryotic Cell Features
- NO NUCLEUS
- NO Internal Organells
- Simple in structure
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Prokaryotic Cell "Structures"
- Cell Membrane
- Cell Wall- rigid structure to provide support/ protect membrane
- Cytoplasm
- Nucleoid- region of "loose DNA"
- Ribosomes
- Cilia- Cell-to-cell communication (how cells identify each other)
- Flagella- Used to move cell, propels cell
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Eukaryotic Cell Features
- CONTAINS NUCLEUS
- Complex in structure
- Contains Organelles (organs inside of cells with membranes)
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Eukaryotic Cell Organelles
- Nucleus
- Endoplasmic Rectulum
- Golgi Apparatus
- Lysosomes
- Vacuole
- Peroxisome
- Mitochandria
- Chloroplast
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Nucleus
Organelle with double-membranes with pours/contains DNA
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Endoplasmic Reticulum
- Organelle that has 2 types
- 1. Smooth ER: produces more membrane, lipids,
2. Rough ER: same as smooth ER but has ribosomes attached and is the only to produce protein
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Golgi Apparatus
Organelle that recieves packages from ER, labels packages and distributes
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Lysosomes
- Organells thats a "Recycling Center" of cell
- breaks down components and determines if components are reusable
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Vacuole
- Organelle that provides "general maintanence"
- Animal- transports food to lysosome
- Plant- stores water
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Peroxisome
- Organelle that acts as "Detox Center"
- converts harmful substances into safe material
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Mitochandria
- Organells with Double Membranes (contains DNA) with ribosomes located in "matrix."
- MAIN FUNCTION- produces energy in cristae, acts as "Power Plant" of all organelles
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Chloroplast
- Organelle with Double Membranes (contains DNA, Ribosomes located in "Stroma")
- Photosynthesis- converts solar energy into food
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What are the Organelles with "Double-Membranes?"
- Nucleus
- Mitochandria
- Chloroplast
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2 Cell Structures of Eurokaryotic Organelles
- Cytoskeleton- "cell skeleton" network of proteins
- Cell Wall- rigid structure of extra support/protection
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Cell Membrane Structure and Components
- 1. Phospholipid Bilayer: 2 layers of phosphate and fat
- - Phosphate is hydrophillic
- - lipid is hydrophobic
- 2. Protein- embedded in layer
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Cell Membrane Protein Components
- Glycoprotein- used for cell-to-cell communication, carb identification
- Receptors- to send/recieve messages
- Enzymes- catalyze reaction
- Transporter- transport substances
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What do Transport Proteins depend on?
Concentration Gradient (must have in order to be transported)
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Small Molecule Transportation (explanation)
- Uses "Passive Transport": moves substances from high concentration to low concentration (moving down gradient)
- Strives to reach equlibrium
- NO ENERGY REQUIREMENT
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Types of "Passive Transport"
- Diffusion- movement of hydrophobic substances
- Osmosis- diffusion of WATER across semipermiable membrane
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3 Types of Osmosis "Tonicity"
- Isotonic- solute concentration is equal between cell and solution (outside of cell)
- Hypotonic- solute concentration of solution (outside of cell) is LOWER than cell
- Hypertonic- solute concentration of solution (outside of cell) is higher than cell
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Osmosis "Tonicity" (def)
Ability of solution to make cell Gain or Lose water.
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Facilitated Diffusion
- Uses transport protein and moves hydrophillic substances
- Aquaporins- proteins that move water
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Active Transport (explanation)
- Movement is Low to High "against gradient"
- REQUIRES ENERGY
- REQUIRES TRANSPORT PROTEINS
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Large Molecule Transportation
- Exocytosis- Exporting out cell (EXIT)
- Endocytosis- Importing into cell (ENTER)
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