phys #13.txt

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What polysaccharide is the gold standard used to measure GFR?

Inulin
What is normal creatine clearance?

80-110 ml
What 4 items are required for the Cockcroft-gault equation?
- 1) Age
- 2) Weight
- 3) Sex
- 4) P_cr
What 4 items are required for the MDRD-4 equation?
- 1) Age
- 2) Sex
- 3) Ethnicity
- 4) P_cr
What is normal Blood urea nitrogen levels (BUN)?

9-18 mg/ml
How much urea is reabsorbed in a normal patient?

1/2
As GFR decreases, how does that affect Urea reabsorption?

Urea reabsorption increases
What is the normal BUN:Cr ratio?

10-15
What is the BUN:Cr ration if a patient persists with 1) Acute tubular necrosis and 2) Nephron loss?

Normal
What is the BUN:Cr ratio in a patient with 1) Dehydration 2) Blood Loss and 3) obstruction?
- High
- ***due to low GFR which causes more reabsorption of urea
What is the BUN:Cr ratio in a patient with 1) Skeletal muscle breakdown 2) Liver disease and 3) malnutrition and why?
- Low
- ** Skeletal breakdown = high Cr
- ** Liver disease and malnutrition = low Urea
What is normal Cr clearance for 1) males and 2) Females?
- 1) Males: 97-140
- 2) Females: 85-125
What type of substance is either less than C_cr (Creatine clearance) or more than Ccr?
- Less = reabsorbed
- More = Secreted
How much glucose is reabsorbed in the kidney?

All of it (0 is secreted)
What does C_x/C_inulin = 1.0 mean?

GFR marker, neither secreted or reabsorbed, but it is filtered completely
What does Cx/Cinulin < 1.0 mean?

either not filtered or filtered and reabsorbed
What does Cx/Cinulin > 1.0 mean?

Filtered and secreted
Why is PAH important?

Some is filtered and the rest is secreted out of plasma
What is PAH a measure of?

RPF since it is secreted out of the plasma
What percentage of RPF reaches the nephrons?

90%
What is the normal Plasma PAH?

1 mg/ml

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kepling

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phys #13.txt

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phys #13

Updated

2011-04-04T23:41:05Z

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