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acetylcholine (ACh)
neurotransmitter active in both the peripheral and central nervous systems.
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acetylcholinesterase (AChE)
enzyme that breaks down acetylcholine bound to post-synaptic receptors within a synapse.
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action potential
electrochemical changes that take place across the axomembrane; the nerve impulse.
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alzheimer disease (AD)
brain disorder characterized by a general loss of mental abilities.
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anygdala
portion of the limbic system that functions to add emotional overtones to memories.
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association area
one of several regions of the cerebral cortex related to memory, reasoning, judgement, and emotional feelings.
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autonomic system
branch of the peripheral nervous system that has control over the internal organs; consists of the sympathetic and parasympathetic systems.
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axon
elongated portion of a neuron that conducts nerve impulses typically from the cell body to the synapse.
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axon terminal
small swelling at the tip of one of many endings of the axon.
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basal nuclei
nerve cells that integrate motor commands to ensure balance and coordination.
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brain
enlarged superior portion of the central nervous system located in the cranial cavity of the skull.
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brain stem
portion of the brain consisting of the medulla oblongata, pons, and midbrain.
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broca's area
region of the frontal lobe that coordinates complex muscular actions of the mouth, tongue, and larynx, making speech possible.
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cell body
portion of a neuron that contains a nucleus and from which dendrites and an axon extend.
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central nervous system (CNS)
portion of the nervous system consisting of the brain and spinal cord.
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cerebellum
part of the brain located posterior to the medulla oblongata and pons that coordinates skeletal muscles to produce smooth, graceful motions.
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cerebral cortex
outer layer of cerebral hemispheres; receives sensory information and controls motor activities.
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cerebral hemisphere
one of the large, paired structures that together constitute the cerebrum of the brain.
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cerebrospinal fluid
fluid found in the ventricles of the brain, in the central canal of the spinal cord, and in association with the meninges.
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cerebrum
main part of the brain consisting of two large masses, or cerebral hemispheres; the largest part of the brain in mammals.
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corpus callosum
bridge of nerve tracts that connects the two cerebral hemispheres.
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cranial nerve
nerve that arises from the brain.
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dendrite
branched ending of a neuron that conducts signals toward the cell body.
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depolarization
when the charge inside the axon changes from positive to negative.
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diencephalon
portion of the brain in the region of the third ventricle that includes the thalamus and hypothalamus.
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dopamine
neurotransmitter in the central nervous system.
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dorsal-root ganglion
mass of sensory neuron cell bodies located in the dorsal root of a spinal nerve.
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drug abuse
dependence on a drug, which assumes an "essential" biochemical role in the body following habituation and tolerance.
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effector
muscle or gland that responds to stimulation.
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episodic memory
capacity of brain to store and retrieve information with regard to persons and events.
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GABA (gamma aminobutyric acid)
major inhibitory neurotransmitter in the CNS.
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ganglia
collections of nerve cell bodies found in the peripheral nervous system.
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ganglion
collection or bundle of neuron cell bodies usually outside the central nervous system.
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glutamate
major excitatory CNS neurotransmitter.
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gray matter
non myelinated axons and cell bodies in the central nervous system.
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hippocampus
portion of the limbic system where memories are stored.
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hypothalamus
part of the brain located below the thalamus that helps regulate the internal environment of the body and produces releasing factors that control the anterior pituitary.
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integration
summing up of excitatory and inhibitory signals by a neuron or by some part of the brain.
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internueron
neuron located within the central nervous system that conveys messages between parts of the central nervous system.
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learning
relatively permanent change in behavior that results from practice and experience.
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limbic system
association of various brain centers, including the amygdala and hippocampus; governs learning and memory and various emotions, such as pleasure, fear, and happiness.
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long-term memory
retention of information that lasts longer than a few minutes.
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long-term potentiation (LTP)
enhanced response at synapses within the hippocampus; likely essential to memory storage.
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medulla oblongata
part of the brain stem that is continuous with the spinal cord; controls heartbeat, blood pressure, breathing, and other vital functions.
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memory
capacity of the brain to store and retrieve information about past sensations and perceptions; essential to learning.
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meninges (sing., meninx)
protective membranous coverings about the central nervous system.
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midbrain
part of the brain located below the thalamus and above the pons; contains reflex centers and tracts.
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motor neuron
nerve cell that conducts nerve impulses away from the central nervous system and innervates effectors (muscles and glands).
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myelin sheath
white, fatty material, derived from the membrane of Schwann cells, that forms a covering for nerve fibers.
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nerve signal
action potential (electrochemical change) traveling along a neuron.
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neuroglia
nonconducting nerve cells that are intimately associated with neurons and function in a supportive capacity.
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neuron
nerve cell that characteristically has three parts; dendrites, cell body, and axon.
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neurotransmitter
chemical stored at the ends of axons that is responsible for transmission across a synapse.
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node of Ranvier
gap in the myelin sheath around a nerve fiber.
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norepinephrine (NE)
neurotransmitter of the postganglionic fibers in the sympathetic division of the autonomic system; also, a hormone produced by the adrenal medulla.
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nuclei
membrane-bounded organelle that contains chromosomes and controls the structure and function of the cell.
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parasympathetic division
that part of the autonomic system that is active under normal conditions; uses acetylcholine as a neurotransmitter.
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parkinson disease
progressive deterioration of the central nervous system due to a deficiency in the neurotransmitter dopamine.
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peripheral nervous system (PNS)
nerves and ganglia that lie outside the central nervous system.
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pons
portion of the brain stem above the medulla oblongata and below the midbrain; assists the medulla oblongata in regulating the breathing rate.
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prefrontal area
association area in the frontal lobe that receives information from other association areas and uses it to reason and plan actions.
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primary somatosensory area
area dorsal to the central sulcus where sensory information arrives from skin and skeletal muscles.
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reflex
automatic, involuntary response of an organism to a stimulus.
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refractory period
time following an action potential when a neuron is unable to conduct another nerve impulse.
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repolarization
when the charge inside the axon resumes a negative charge.
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resting potential
polarity across the plasma membrane of a resting neuron due to an unequal distribution of ions.
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reticular formation
complex network of nerve fibers within the central nervous system that arouses the cerebrum.
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saltatory conduction
movement of nerve impulses from one neurofibril node to another along a myelinated axon.
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Schwann cell
cell that surrounds a fiber of peripheral nerve and forms the myelin sheath.
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semantic memory
capacity of the brain to store and retrieve information with regard to words or numbers.
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sensory neuron
nerve cell that transmits nerve impulses to the central nervous system after a sensory receptor has been stimulated.
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sensory receptor
structure that receives either external or internal environmental stimuli and is a part of a sensory neuron or transmits signals to a sensory neuron.
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serotonin
a neurotransmitter
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short-term memory
retention of information for only a few minutes, such as remembering a telephone number.
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skill memory
capacity of the brain to store and retrieve information necessary to perform motor activities, such as riding a bike.
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sodium-potassium pump
carrier protein in the plasma membrane that moves sodium tons out of and potassium ions into cells; important in nerve and muscle cells.
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somatic system
that portion of the peripheral nervous system containing motor neurons that control skeletal muscles.
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spinal cord
part of the central nervous system; the nerve cord that is continuous with the base of the brain plus the vertebral column that protects the nerve cord.
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spinal nerve
nerve that arises from the spinal cord.
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stimulus
change in the internal or external environment that a sensory receptor can detect, leading to nerve impulses in sensory neurons.
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sympathetic division
the part of the autonomic system that usually promotes activities associated with emergency (fight or flight) situations; uses norepinephrine as a neurotransmitter.
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synapse
junction between neurons consisting of the presynaptic (axon) membrane, the synaptic cleft, and the post synaptic (usually dendrite) membrane.
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synaptic cleft
small gap between presynaptic and post synaptic membranes of a synapse.
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thalamus
part of the brain located in the lateral walls of the third ventricle that serves the integrating center for sensory input; it plays a role in arousing the cerebral cortex.
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threshold
electrical potential level (voltage) at which an action potential or nerve impulse is produced.
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tract
bundle of myelinated axons in the central nervous system.
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ventricle
cavity in an organ, such as a lower chamber of the heart or the ventricles of the brain.
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Wernicke's area
brain area involved in language comprehension.
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white matter
myelinated axons in the central nervous system.
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