What was the cause of conflicts between Southern colonists and their Native American neighbors?
The cause of conflicts between the Southern colonists and their Native American neighbors was that the settlers kept pushing the Native Americans off their lands. They would build their settlements on Native American lands and would destory their villages. This led to conflicts and wars. One such war was The Tuscarora War which lasted for several years and ended in about 950 Tuscarora being killed or captured and sold as slaves.