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pharm exam 2
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an additional therapy given to enhance or extend the effect of the primary therapy
adjuvant
substances liberated by the body during phases of inflammation that can produce pain
algongenic substances
insensibility to pain without loss of consciousness
analgesia
agents that relieve pain by inhibitn specific pain pathways
analgesics
capable of reducing fever
antipyretic
originating or producing within the organism or one of its parts
endogenous
equal in the ability for giving pain relife
equianalgesic
a test to determine risk of bleeding
international normalized ration (INR)
reduction of circulation to an area
ischemia
an initial high dose to quickly achieve a therapeutic blood level
loading dose
sensory detection and neuronal transmission of pain stimuli
nociception
injuious or harmful
noxious
derived from opium a strong dependence producing analgesic
opioid
characterist or indicativ (diagnostic) of a particular disease or condition
pathognomonic
pain caused by the activation of pain receptors in mucocutaneous and musculoskeletal tissues
somatic pain
pain caused by the activation of pain receptors in internal organs
visceral pain
AA
arachidonic acid
APAPAPAPAPAPA
acetaminophen
ASA
Aspirin
COX
cyclooxygenase
COX 1
cyclooxygenic inhibitors
LP
Lipoxygenase
NSAIDs
nonsteroidal anti inflammatory drugs
what is the most common cause to make a pt seek dental services?
PAIN
All of the following endogenous peptides will relieve
pain except one. Which one is the exception?
A) Enkephalins
B) Dynorphins
C) Endorphins
D) Prostaglandins
D) prostaglandins
what is the most commonly prescribed drug for orofacial pain?
hydrocodone with APAP
when do you use a narcotic versus a nonnarcotic?
depends on the pt pain perception
what is given to people with severe pain?
cox 1 or 3 with oxycodone
what is given to pt with moderate dental pain?
cox 1 inhibitors either alone with APAP or with codeine
t/f APAP can be given to a prego pt
True
False
true
t/f all cox inhibitors increase pain threshold
True
False
true
ASA, ibuprophen, naporoxen and naproxen Na are all examples of what type of inhibitors?
cox 1
where are cox 1 expressed?
in all normal tissues
t/f cox 1 increase bleeding
True
False
true
t/f cox 1 protects gastric mucosa and causes gastric irritation
True
False
true? I dunno jackie those notes seem a little weird but it was in red so i had to put it
where are cox 2 expressed?
primarily in brain, kidneys and female reproduction system and bone
what is the action of cox 2 inhibitors?
raise pain threshold
cox 2 inhibitors block endothelial prostacycline synthesis to cause? 2
blood clots
vasoconstriction
where are cox 3 expressed?
CNS
what is an example of cox 3
APAP (tylenol)
what is an example of cox 2 inhibitor?
celebrex
t/f cox 3 has no anti inflammatory effect
True
False
true
t/f cox 3 has analgesic and antipyretic effect
True
False
true inhibt prostaglandin in CNS
t/f APAP has effect on the platelet function
True
False
FALSE NO NO NO effect on platelet function. blah blah blah I am so sick of pharm!
with 500mg of aspirin what happens to bleeding times?
prolongs bleeding times (8 days)
what is the prototype of penicillin?
penicillin G
what antibiotic is prone to resistance (immunity common)?
erythromycin
when do you give premed? 7
cardiac conditions
aritificial heart valves
specific congenital heart defects
unrepaired or incompletely repaired cyanotic congenital heart disease (shunts and conduits)
completely repaired congenital hear defect with prosthetic material or device during the 1st 6 moths of post surgery
repaired congenital heart defect with residual defect at site or adjacent to site of prostheic patch or device
cardiac transplant that develops valvuar problems
you give premed for a cardiac transplant that has no problems
no only if vavlular problems
t/f premed is needed for cardiac conditions
True
False
true
t/f no pre med is needed for artificial heart valves
True
False
false premed needed
what interacts with antibiotics? 3
oral contraceptives
rifampin (for TB)
pseudomembranous colitis
if stool appears black while taking antibiotics what should you do?
STOP antibiotics
with what antibiotics do you develop pseudomembranous colitis?
clindamycin and lincomycin
Author
cassiedh
ID
73862
Card Set
pharm exam 2
Description
chapter 8 objectives and review
Updated
2011-03-20T00:19:37Z
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