Lidocaine (Xylocaine)

  1. Class
  2. Description
    Amide-type local anesthetic, Frequently used to treat life threating dysrhythmias
  3. Mechanism of Action
    Suppresses ventricular ectopic activity, raises ventricular fibrillation threshold, reduces velocity of electrical impulses through conductive system
  4. Onset of Action
    • Onset: <3 minutes
    • Peak: 5-7 minutes
    • Duration: 10-20 minutes
    • Half-Life: 1.5-2.0 hours
  5. Indications
    Malignant PVCs, pulseless V-Tach, V-Fib, V-Tach w/ pulse, Prophylaxis of dysrhythmias with fibrinolytic therapy
  6. Contraindications
    High degree heart block, PVC’s in conjunction with bradycardia
  7. Precautions
    Monitor for central nervous system toxicity
  8. Side effects
    (In alphabetical order for Rory)
    Anxiety, confusion, convulsions, dizziness, drowsiness, nausea, vomiting, widening of QRS complex
  9. Adult dose
    • Cardiac arrest (vfib/pulseless vtach): 1.0-1.5 mg/kg IV bolus up to 3 mg. If rhythm is converted start maintenance infusion.
    • Vtach w/ pulse: 0.5 - 1 mg/kg may be repeated 3-5 min until dysrhythmia is controlled or 3 mg/kg has been given. If rhythm is converted start maintenance infusion.
    • Pts over 70 and/or with liver disease: reduce dose by 50%.
  10. Pedi dose
  11. Max dose
  12. Drips
    Maintenance infusion: After dysrhythmia is suppressed, a 2-4 mg/min infusion may be started to maintain adequate blood level
  13. Routes of Administration
    IV bolus, IV infusion
  14. How supplied
    Prefilled syringes and vials
Card Set
Lidocaine (Xylocaine)
Paramedic drugs