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Two groups of organs:
- alimentary canal (gastrointinal or GI tract)
- accessory digestive organs
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Alimentary canal (gastrointestinal or GI tract) includes:
- mouth
- pharyn
- esophagus
- stomach
- small intestine
- large intestine
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Alimentary canal (gastrointestinal or GI tract) does what to food?
digest and absorbs food
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Accessory digestive organs include:
- teeth
- tongue
- bladder
- digestive glands
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Digestive glands include:
- salivary glands
- liver
- pancreas
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6 essential activities of digestive processes:
- ingestion
- propulsion
- mechanical digestion
- chemeical digestion
- absorption
- defecation
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Adjacent segments of alimentary tract organs alternately contract and relax, which moves food along the tract distally.
peristalsis
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Nonadjacent segments of alimentary tract organs alternately contract and relax, movign food forward then backward. Food mixing and slow food propulation occurs.
segmentation
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Serious membrame of the abdominal cavity.
peritoneum
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Peritoneum includes:
- visceral peritoneum: on external surface of most digestive organs
- partietal peritoneum: lines the body wall
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Peritoneal cavity is found _____ the two _____. And _____ lubricates mobile _____.
- between
- peritoneums
- fluid
- organs
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Double layer of peritoneum.
mesentary
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Two functions of the mesentary:
- routes for blood vessels, lymphatics, and nerves
- holds organs in place and stores fat
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Organs that lie posterior to the peritoneum.
retroperitoneal
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Organs that are surrounded by the peritoneum.
intraperitoneal (peritoneal)
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Fout basic layers (tunics):
- mucosa
- submucosa
- muscularis externa
- serosa and/or adventitia
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The mucosa lines the _____.
lumen
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Three functions of mucosa:
- secretes mucus, digestive enzymes and hormones
- absorbs end products of digestion
- protects against infectious disease
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Three sublayers of mucosa:
- epithelium
- lamina propria
- muscularis mucosae
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Simple columnar epithelium and mucus-secreting cells; may secrete enzymes and hormones (e.g., in stomach and small intestine)
epithelium mucosa
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Two functions of epithelium mucosa:
- protects digestive organs from enzymes
- eases food passage
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Loose areolar connective tissue.
lamina propria mucosa
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Lamina propria mucosa are capillaries for _____ and _____; also lymphoid _____.
- nourishment
- absorption
- follicles
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Smooth muscle that produces local movements of mucosa.
muscularis mucosae
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Dense connective tissue. Includes: blood and lymphatic vessels, lymphoid follicles, and submuscosal nerve plexus
submucosa
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Responsible for segmentation and peristalsis. Includes inner circular and outer longitudinal layers, myenteric nerve plexus and sphincters in some regions.
muscularis externa
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Replaces by the fibrous adventitia in the esophagus. Retropertitoneal organs have both an adventitia and serosa.
visceral peritoneum
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Bounded by lips, cheeks, palate, and tongue. Oral orifice is the anterior opening. Lined with stratified squamous epithelium.
oral (buccal) cavity
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Contains orbicularis oris, and buccinator muscles, vestibule, labial frenulum and oral cavity proper lies within the teeth and gums.
lips and cheeks
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Recess internal to lips and cheeks, external to teeth and gums.
vestibule
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Median attachment of each lip to the gum.
labial frenulum
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Palatine boes and palatine procces of the maxillae; slightly corrugated to help create friction against the tongue.
hard palate
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Fold formed mostly of skeletal muscle; closes off the nasopharynx during swallowing and uvula projects downward from its free edge
soft palate
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Three functions of the tongue:
- repositioning and mixing food during chewing
- formation of the bolus
- initiation of swallong, speech, and taste
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Part of tongue that attaches to the floor of the mouth.
lingual frenulum
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Three types of salivary glands:
- extrinsic
- intrinsic (buccal)
- secretion (saliva)
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Glands found in parotid, submandibular, and sublingual.
extrinsic salivary glands
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Glands that are scattered in the oral mucosa.
intrinsic (buccal) glands
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Four fucntions of secretion (saliva):
- cleanses the mouth
- moistens and dissolves food chemicals
- aids in bolus formation
- contains enzymes that begin the breakdown of starch
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Primary and permanent dentitions are formed by age ___.
21
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Erupts at 6-24 months of age (20 of them); and roots are resorbed, teeth fall out at 6-12 years as permanent teeth develop.
deciduous teeth
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All except third molars erupt by the end of adolescence (32 of them)
permanent
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Chisel shpaed for cutting.
incisors
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Fanglike teeth that tear or pierce.
canines
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Have broad crowns with rounded cusps for grinding or crushing
- premolars (bicuspids)
- molars
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The exposed part above the gingiva (gum).
crown
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The crown is covered by _____ which is the hardest substance in the body (calcium salts and hydroxyapatite crystals)
enamel
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Portion embedded in the jawbone; connected to crown and neck.
root
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Calcified connective tissue; covers root and attaches it to the periodontal.
cementum
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Forms fibrious joint called a gomphosis.
periodontal ligament
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Groove where gingiva borders the tooth.
gingival sulcus
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Bonelike material under enamel; maintained by odontoblasts of pulp cavity.
dentin
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Cavity surrounded by dentin.
pulp cavity
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Connective tissue, blood vessels, and nerves.
pulp
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Extends from pulp cavity to the apical foramen of the root.
root canal
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Allows passage of food, fluids, and air; stratified squamous epithelium lining; made up skeletal muscle layers.
oropharynx and laryngopharynx
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Inner longitudinal, outer pharyngeal constrictors.
skeletal muscle layers of pharynx
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Flat muscular tube from laryngopharynx to the diaphragm to the gastroesophageal sphincter in the superior aspect of the stomach; approximately 25cm long; has adventitia instead of serosa.
esophagus (gullet)
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Four digestive processes of the mouth:
- ingestion
- mechanical digsestion
- chemical digestion
- propulsion
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Mastication is partly voluntary, partly reflexive.
mechanical digestion
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Contains salivary amylase and lingual lipase.
chemical digestion
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Deglutition (swallowing).
Propulsion
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The parts of the stomach's gross anatomy:
- cardiac region (cardia)
- fundus
- body
- pyloric region
- lesser/greater curvation
- leser/greater omentum
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Surrounds the cardiac orifice.
cardiac region
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Dome-shaped region beneath the diaphragm.
Fundus
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Midportion of stomach.
body
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Antrum, pyloric canal, and pylorus; pylorus is continuous with the duodenum thorugh the pyloric valve (sphincter).
pyloric region
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Convex lateral surface.
greater curvature
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Concave medial surface.
lesser curvature
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From the liver to the lesser curvature.
greater omentum
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Drapes from greater curvature; anterior to the small intestine
greater omentum
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Three factors of stomach anatomy:
- four tunics
- muscularis and mucosa are modified
- mucosa
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Three layers of smooth muscle; inner oblique layer allows stomach to churn, mix, move, and physically break down food.
muscularis externa
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Simple columnar epithelium composed of mucous cells; layer of mucus traps bicarbonate-rich fluid beneath it; gastric pits lead into gastric glands
mucosa
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Four cell types of gastric glands:
- mucous neck cells (secrete thin, acidic mucus
- parietal cells - HCL
- chief cells - pepsinogen
- enteroendocrine cells
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Major organ of digestion and absorption; 2-4m long; from pyloric sphincter to ileocecal valve; has subdivision.
small intestine
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Subdivision of small intestines:
- duedenum (retroperitoneal)
- jejunum (attached posteriorly by mesentery)
- ileum (attached posteriorly by mesentery)
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The bile duct and main pancreatic duct. Joined at the hepatopancreatic ampulla, enters the duodenum at the major duodenal papilla and are controlled by the hepatopancreatic sphincter.
Duodenum
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What three factors increases surface area of proximal part for nutrient absorption?
- circular folds (plicae circulares)
- villi
- microvilli
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Motile fingerlike extension (~1mm high) of the mucosa. Includes villus epithelium; simple columnar absorptive cells (enterocytes) and globelet cells.
villi
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Projections (brush border) of absorptive cells; bear brush border enzymes.
microvilli
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Secretory cells that produce intestinal juice; enteroendocrine cells; intraepithelial lymphocytes (IELs); paneth cells; stem cells
intestinal crypt epithelium
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Release cytokines that kill infected cells
intraepithelial lymphocytes (IELs)
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Secretes antimicrobial agents (defensis and lysozyme).
paneth cells
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Peyer's patches protect distal part against bacteria; duodenal (Brunner's) glands of the duodenum secrete alkaline mucus.
submusoca
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Largest gland in the body; four lobes - right, left, caudate,a nd quadrate.
liver
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Separates the (larger) right and (smaller) left lobes; suspends liver from the diaphragm and anterior abdominal wall.
falciform ligament of liver
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Remnant of fetal umbilical vein along free edge of falciform ligament.
round ligament (ligamentum teres) of liver
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Three types of ssociated structures of liver:
- lesser omentum anchors liver to stomach
- hepatic artery and vein at the porta hepatis
- bile ducts
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Common hepatic duct leaves the liver; cystic duct connects to gallbladder; formed by the union of the above two ducts.
bile ducts
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Two factors of liver lobules:
- hexagonal structural and functional units
- longitudinal central vein
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Filter and process nutrient-rich blood; composed of plates of hepatocytes (liver cells).
hexagonal structural and functional units of liver lobules
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Bile duct receives bile from bile canaliculi; portal arteriole is a branch of the hepatic artery; hepatic venule is a branch of the hepatic portal vein.
portal triad at each corner of lobule
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Leaky capillaries between hepatic plates
liver sinusoids
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(hepatic macrophages) in liver sinusoids.
Kupffer cells
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Four functions of hepatocytes:
- process bloodborne nutrients
- store fat-soluble vitamins
- perform detoxification
- produce ~900ml bile per day
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Yellow-gree, alkaline solution containing bile salts, bilirubin, cholesterol, neutral fats, phopholipids and electrolytes.
bile
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Cholesterol derivatives that function in fat emulsification and absorption.
bile salts
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Pigment formed from heme.
bilirubin
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Thin-walled muscular sac on the ventral surface of liver; stores and concentrates bile by absorbing its water ions; releases bile via the cystic duct, which flows into the bile duct.
gallbladder
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