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WHAT IS THE PARASYMPATHETIC NEUROTRANSMITTER?
ACETYLCHOLINE
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WHAT IS THE PHARMACOLOGICAL EFFECTS OF PARA?
CHOLINERGIC
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WHAT IS THE FUNCTIONAL CHARACTERISTICS OF PARA?
CONSERVATION---RESTAURATION
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WHAT ARE THE RECEPTORS OF SYMPA?
ALPHA 1,2 & BETA 1,2
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WHAT IS THE PHARMACOLOGICAL EFFECTS OF SYMPA?
ADRENERGETIC
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WHAT IS THE NEUROTRANSMITTER OF SYMPA?
NOREPINEPHRINE
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WHAT ARE THE SIDE EFFECTS OF CHOLINERGICS?
- VOMIT
- DIAHRREA
- REDUCES HR
- DECREASES BP
- SWEAT
- SALIVATION
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WHAT ARE THE NAME OF THE TWO CHOLINERGIC DRUGS?
NEO AND PILO
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WHAT IS THE CLINICAL USES FOR PILO?
EYE-DROP IN OPEN ANGLE GLAUCOMA
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WHAT IS " NEO" CLINICAL USES?
- ANTIDOTE- FOR CURARE*
- STIMULATE MUSCLE TONE MG
- ATOMIC INTESTINE AND BLADDER
-
CHOLINERGIC STIMULARTES....?
PARA-MIMETIC
-
ANTI-CHOLINERGIC BLOCKS..?
PARA--LYTIC
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ANTI-CHOLINERGIC PHARMALOGICAL EFFECTS?
- RELAX MUSCLE
- INHIBITS DUC GLANDS
- DILATE PUPILS
- PARALYSE ACCOMODATION MUSCLES
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WHYS IS ANTI-CHOL IS USES AS PRE ANESTHESIC?
TO REDUCE SALIVATION DURING OPERATION
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I WHAT DISORDER ANTI-CHOLI HELPS TO REGULATE MUSCLE CONTROL?
PARKINSON'S DISEASE.
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WHAT ARE THE TWO CONDITION WHERE ANTI-CHOL IS CONTRAINDICATED?
- NARROW ANGLE GLAUCOMA
- PROSTATIC HYPERTROPHY
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WHAT ARE THE NAMES OF THE TWO ANTI-CHOL DRUGS?
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WHAT IS THE CLINICAL USE FOR SCOLPO?
MOTION SICKNESS --PATCH
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WHAT IS THE CLINICAL USE FOR ANTROPINE?
BRADYCARDIA
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WHAT ARE THE PRECAUTIONS OF CORTICOIDS?
- DIABETES
- PEPTIC ULCER
- HYPERTENTION-= CAUSES Na RETENTION
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WHAT TYPE OF DM DOENST NEED INSULIN?
TYPE II IS NIDDM
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WHAT IS KITOACIDOSE?
TOO MUCH KITONES PRODUCED IN BODY DUE TO FAST METABOLISM
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WHAT DRUG INHIBITS INSULIN?
- GLUCORTICOIDS
- EPINEPRHINE
- THYROID HORMONES
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GIVE 3 SYMPTOMS OF DM?
- HYPERGLYCEMIA
- POLYURIA
- POLYDSYA
- THIRSTY.. EXCESSIVE URINATION
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WHAT ARE THE MAIN ORGANS THAT DM DAMAGES?
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WHAT ARE THE CHARACTERISTIC OF GLARGINE LANTUS INSULIN?
- STAY LEVELED
- CAN'T BE MIXED
- LONG ACTING
- DONT HAVE ANY PICKS
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WHAT INSULIN COME IN SUSPENTION FORM?
CLAUDY" LANTUS
LONG ACTING
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WHAT INSULIN MUST BE DRAWN FIRST?
- FAST ACTING, OR NPH
- TO AVOIND CONTAMINATION WHEN MIXING WITH SLOW ACTING
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WHAT INSULIN IS SLOW ACTING?
REGULAR
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WHAT DRUGS AFFECT INSULIN DOSAGE?
SITAGLIPIN
INCREASE SYNTHESIS OF INSULIN REDUCING LIVER GLUCOSE PRODUCTION
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WHAT IS THE INSULIN OVERDOSE ANTIDOTE?
GLUCAGON
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COMPLICATION OF ISULIN OVERDOSE?
HYPOGLYCEMIA
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WHAT ARE THE SIGNS OF HYPOGLYCEMIA?
- SWEATY
- NERVOUSNESS
- DIZZINESS
- WEAKNESS
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WHAT ARE THE ADVERSE EFF. OF SITAGLIPIN?
- HA
- PHARINGITIS
- UTRI
- HYPOGLYCEMIA
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WHAT ORAL DM DRUG DECREASES GLUCOSE PRODUCTION IN THE LIVER ?
METFORMIN
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WHAT ARE THE DIFFERENCES IN GLYBURIDE 2ND GENERATION OF SULFONYUREA?
- LESS DDI
- LESS ALCOHOL SENSITIVITY
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WHAT ORAL DM DRUG CAUSES GI DISTRESS, VIT. DEF. AND LACTIC ACIDOSE?
METFORMIN
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WHAT MD ORAL DRUG CAUSES URTI--EDEMA--HA-- WEIGHT GAIN?
PIOGLITAZONE
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WHAT MD DRUG CAUSES GNS AND ANEMIA?
ARCABOSE
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WHAT MD DRUG SLOWS DOWN ACTIVITY OF INCRETIN?
SITAGLIPIN
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RENAL DYSFUNCTION OCCURS IF PT OVERDOSE OF WHAT MD DRUG?
SITA
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WHAT MD DRUG CAN BE USED AS ADJUNCTIVE THERAPY OT TREAT TYPE I & II DM?
PRAMLINTIDE
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WHAT IS THE DRU-DRUG INTERACTION OF PRAMLINTIDE?
DO NOT MIX WITH INSULIN!
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WHAT ARE THE ADV. EFF'S OF PRAM?
- HYPOGLYCEMIA
- N/V
- ALLERGY
- HA
- DIZZINESS
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WHAT IS THE NAME OF THE DISEASE THAT MAKE BODY PRODUCE TOO MUCH CORTISOL?
HYPERTHYROIDISM
-
WHAT ARE THE 3 CLASS OF HORMONES SYNTHESIZED IN ADRENAL CORTEX
- GLUCACORTICOIDS
- MINERALOCORTICOIDS- ALDOSTERONE
- ANDROGENS
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WHAT IS THE PHARMACOLOGICAL EFFECTS OF GLUCORTICOIDS DRUGS
- METABOLIC (FAT, CHO, PROTEIN METABOLISM)
- ANTI-INFLAMMATORY
- IMMUNOSUPPRESSIVE
- SODIUM RETENTION WITH POTASSIUM LOSS
-
WHAT IS THE PRECAUTION OF CORTICOTICOIDS IN DIABETES?
DECREASE BLOOD SUGAR
-
SIDE EFFECTS OD GLUCOCORTICOIDS?
- DRUG INDUCE ==CUSHING'S SYNDROME
- HYPERGLYCEMIA
- MOOD CHANGES
- OSTEOPOROSIS
- PEPTIC ULCER
- INCREASE SUCEPT. TO INFECTION
- GI UPSET
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CLINICAL USES OF GLUCACORTICOIDS?
- REPLACEMENT THERAPY- INSUF. PROD. OF CORTISONE
- ANTI-INFLAMMATORY--STEROIDS
- ALLERGIC STATES--ASHMA
- COLLAGEN DISEASE SLE-- LUPUS, PRURITS
- NEOPLASTIC- CANCER
- RHEUMATIC
- GI- ULCERATIVE COLITIS
-
ADRENAL SUPPRESSION OCCURS WHEN?
SUDDEN WITHDRAWAL OF STEROIDS--CAUSE ADRENAL INSUFFICIENCY
-
WHAT CAN BE DONE TO MINIMIZE ADRENAL SUPPRESSION DURING GLUCO CORTICOID LONG TERM THERAPY?
- ALTERNATE DAY THERAPY
- EARLY MORNING ADMINISTRATION
-
WHAT ARE THE DISEASE RELATED T GLUCORTICOIDES DRUGS?
- ADRENAL INSUFFICIENCY--ADDISON'S DISEASE= NOT ENOUGH CORTISOL PRODUCTION
- OVERPRODUCTION OF CORTISOL-- CUSHING'S DISEASE---
-
WHAT ARE THE DRUG-DRUG INTERACTION OF GLUCORTICOIDS?
- ORAL ANTICOAGULANTES
- ANTIDIABETES
- SALICYTATES-ASPIRIN
-
HYDROCORTISONE
- SHORT ACTING
- LIKE NATURAL HORMONE IN ACTIVITY
- TAKE WITH MEALS
- LEAST POTENT
-
PREDNISONE(ORAL)-- AND METHYLPREDINISONE (INJECTABLE)
- INTERMEDIAN ACTING
- MORE ANTI-INFLAMMATORY
- LESS SODIUM RETENTION
-
TRIAMCINOLONE (ARTISTOCORT)
- INTERMEDIAN ACTING
- USED IN
- ORTHOPEDICS
- DERMATOLOGY
- INHALERS
-
DEXAMETHASONE (DECADRON)
- LONG ACTING
- POTENT ANTIFLAMATORY
- NO SODIUM RETENTION
- TREAT- CEREBRAL EDEMA
-
WHAT ARE TH MAJOR FACTOR THAT CAUSES DM?
-
WHAT ARE THE TWO TYPES OF TYROID HORMONES?
THYROXINE T4
TRIIODOTHYRONINE T3
-
CRETINISM
- HYPOTHYROID-- CONGENITAL FORM
- COMMON CAUSE INFLAMATION
-
MYXEDEMA
- HYPOTHYROID
- LACK OF ENERGY, PUFFY FACE, WEIGHT GAIN, SENSITIVITY TO COLD, MUSCLE WEAKNESS
-
DRUGS USED IN HYPOTHYROIDISM
- TYROID DESSICATE
- LEVOTHYROXINE
- LIOTHYRONINE
-
THYROID DESSICATE
- ANIMAL GLAND
- VARIABILITY IN POTENCY--MAIN PROBLEM
- INEXPENSIVE
-
LEVOTHYROXINE
DRUG OF CHOICE-- ONE A DAY ONLY
- CONVERTS TO T3 IN BODY
- ADV. EFFECTS
- STIMULATION OF HEART,GI
- INSOMIA
- WEIGHT LOSS
- ---LONG HALF -*LIFE
-
WHAT IS THE PREUCATION OF LEVO?
HEART DISEASE PT'S
-
LIOTHYRONINE
NOT GOOD PT COMPLIANCE
- REQUIRE MULTIPLE DOSES
- DIFFICULT TO MONITOR LEVELS
- MORE CARDIAC ADVERSE EFF.
- SHORT HALF-LIFE
-
HYPERTHYROIDISM
EXCESS OF THYROID HORMONES ARE REALEASED
-
WHAT TYPE OF HYPERTHYROID DISORDER CAUSES-- CARDIAC STIMULATION, WEIGHT LOSS, RESTLESSNESS, AND BULGING EYES?
GRAVE'S DISEASE
-
TREATMENT FOR HYPERTHYROIDISM
PROPHYLTHIURACIL (PTU)
- INHIBITS THE SYNTHESIS OF THYROID HORMONES- BLOCKS THYROCIADASE
- IF WELL CONTROLLED, 6-12MONTHS-- MAY TRY TO DISCONTINUE DRUG
-
ADVERSE EFFECTS OF PROPHYLTHIURACIL (PTU) ?
- LOSS OF TASTE
- N/V
- DIZZINESS
- LEUKOPENIA
- AGRANULOCYTOSIS
- __PRECAUTION IN PREGNACY-- IT CROSS BBB
-
WHAT IS THE PREUCATION WITH DRUG-DRUG INTERACTION WIHT GRAVIS DISEASE?
- WAFARIN- CUMADIN
- HIGLY PROTEIN BODING
-
WHAT HYPO DRUG HAS THE LONGEST HALF LIFE AND NOT SODIUM RETENTION?
LEVO
-
WHAT ARE THE 3 TREATMENTS FOR HYPERTHYROID?
- DRUG PROPYL (PTU)
- RADIOACTIVE IODINE
- SURGERY
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