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Name and describe functions of bone tissue.
- Support – framework
- Protection – Bone marrow and organs. (axial skel has cranial bones & thoracic cage.)
- Leverage – long bones esp. Long bones give more power for effort
- Storage – Minerals and lipids.
- Minerals - calcium and phosphate.
- Lipids – energy reserves in areas filled with yellow marrow.
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Name and describe the major bones shape categories and give an example of a bone in each.
- Long Bones – femur
- Short Bones – talus
- Irregular Bones – sphenoid
- Sesamoid Bones – patella
- Flat Bones – occipital bone
- Sutural Bones – often found within the sutures of flat bones in skull
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How does its tissue arrangement differ from cancellous (spongy) bone?
- Compact or dense bone is
- organized in osteons and is stronger and heavier than spongy bone.
- Stronger so it can withstand more stress than spongy bone.
- found on the surface of all bones.
- slower to form.
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Name the 4 types of bone cells and describe what each one does
- Osteoprogenator Cells – Stem cells which can divide quickly. Important for growing and healing.
- Osteoblast Cells – produce bone matrix – collagen and other organic bone components (osteoid)
- Osteocyte – Mature bone cells that sit in lacunae. They maintain the bone matrix
- Osteoclast – Macrophages (a monocyte (mononuclear phagocytic WBC) that has left circulation and settled and matured in tissue. There are a variety of macrophages found throughout the body.) These are the “cleanup” cells.
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What is intramembranous ossification?
- bone developes directly from mesenchyme or fibrous connective tissue.
- happens in ossification center
- bone grows from center outward forming spicules.
- Blood vessels grow into area and become trapped as bone develops.
- Osteons and periosteum forms
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What is an osteoid?
prebone; resembles bone
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What cells are involved in intramembranous ossification?
- CT cells,
- Osteoprogenator
- Osteoblasts
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What is endochondral ossification? (Always)
- most common process of bone formation.
- bone is formed within hyaline cartilage
- gradual process that continues as long as cartilage remains.
- As long as growth plate has cartilage, bone can lengthen.
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What are the 5 steps of Endochondral ossification?
- 1. Chondrocytes enlarge near ctr of shaft, calcium is added to the matrix and chondrocytes cant get nutrients so they start dying
- 2. increased blood vessel growth in perichondrium, perichondrium cells chg to osteoblast producing a periosteum
- 3. Primary ossification ctr develops near middle of model - capillaries and fibroblast move into ctr of cartilage
- 4. Remodeling begins - osteoclasts carve out a marrow cavity, spongy remodels to compact, epiphyseal cartilage growth continues
- 5. Development of bone in epiphysis - blood vessels enter epiphysis allowing 2nd ossification ctr to begin forming. Same process as primary EXCEPT spongy bone is left in epiphyses.
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What could be results of epiphyseal plate damage?
the amount of cartilage at the growth plate could be reduced thus will be converted to bone sooner than normal.
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What are the 4 steps in healing a fractured bone?
- 1. Blood clot forms to stabilize break
- 2. fibroblasts move in from periosteum forming external callus, fibroblast from endosteum form internal callus, fibroblasts produce collagen to knit bone together
- 3. Callus convert to bone - osteoblast replace cartilage w/ bone, external and internal callus tissues connect
- 4. osteoblasts and clasts remodel area, attempting to regain orig shape.
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Explain how bones gain diameter
by osteoprogenators and osteoblasts. Marrow cavity is enlarged by osteoclasts
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What is bone remodeling?
part of normal bone maintenance where the organic and mineral components of the bone matrix are being recycled. Also takes place to reshape after injury.
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List the facial bones
- Mandible
- Maxillae
- Palatine bones
- Nasal bones
- zygomatic bones
- lacrimal bones
- inferior nasal concha
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what bone and structure does the condylar process of the mandible fit into?
mandibular fossae of temporal bones
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What do paranasal sinuses do?
lighten skull and resinate sound
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what are the names of the normal curves of the vertebral column and where is each located?
- Cervical curve - Anterior Curve
- Thoracic Curve - posterior curve
- Lumbar Curve - anterior curve
- Sacral Curve - posterior curve
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Name 3 abnormal vertebral curves
- kyphosis- hump back
- lordosis - bending backwards
- scoliosis - side to side curving
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What pairs of ribs articulate directly with the sternum?
pairs 1 - 7
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Which ribs do not articulate with the sternum at all?
prs 11 and 12. they are called floating ribs
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name the joint between the pelvic girdle and the axial skeleton
sacroiliac joint
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What 2 bones and parts of these bones make up the ankle?
- Tibia and the medial malleolus
- Fibula and the lateral malleolus
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What is the heel bone called?
Calcaneus
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What are the cells involved in remodeling process and what do they do?
- Osteoclast - clean-up
- Osteoblast - build
- osteocytes - maintain
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What vitamins are needed for bone growth and what happens in the case of deficiency?
- Vit C (needed for collagen) - deficiency = scurvy (brittle bones)
- Vit D (needed for calcium absorption) - deficiency = rickets (soft bones
- Calcium (needed to harden bones)
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What are some of calcium's uses?
- blood clotting
- muscle contraction
- neural signaling
- co-enzyme use
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What are the 2 hormones involved in restoring calcium balance and what do each do?
- Calcitonin - used to lower calcium in blood by decreasing absorption in GI tract, kidneys allow more loss, keep bones from releasing store calcium into system.
- Parathyroid hormone - stimulates osteoclasts to release calcium from bone, decrease rate of excretion at kidneys, increase rate of absorption in GI tract
- calcitriol - Active form of Vit. D - allows for greater absorption in GI tract and in kidneys
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What is the bones role in blood cell production?
All types of blood cells are produced in red bone marrow
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What is a comminuted fracture?
Shattered
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What is a stress fracture?
Cracking in bone due to repeated stress
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process
projection or bump
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facet
small, articular surface
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meatus
passage or opening
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condyle
smooth rounded articular process
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sinus
open area within a bone
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head
expanded articular end of an epiphysis
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trochanter
lg rough projection
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tubercle
small rounded projection
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ramus
extension of bone that makes an angle with the rest of the structure
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