Dyslipidemia starts as a _______ disorder and ends as an ___________ response.
"lipid"
"inflammatory"
What is a foam cell?
A macrophage full of engulfed lipids.
Glucocorticoids, androgens, estrogens, aldosterone, and phospholipid stabilizers all have what in common?
They are all made from cholesterol.
True or false?
Apoproteins cleave triglycerides from lipoproteins.
False.
Apoproteins are important flags for various receptors/enzymes. Lipoprotein lipase cleaves triglycerides from lipoproteins.
What are some sources of cholesterol for our body?
Diet
Synthesis by the liver and adrenals
What are some avenues of elimination for cholesterol in our bodies?
Bile
Feces
What transporters carry dietary fat from the intestines to the tissues?
Chylomicrons
The ratio of trigs. to cholesterol in a chylomicron is...
10:1
What apoprotein serves as a flag for chylomicrons to be picked up by the liver?
ApoB48
Which lipoprotein carries fatty acids from the liver to muscle and adipose? Trigs:cholesterol ratio? What apoprotein flags it for pick-up by the liver? What apoprotein flags it for trig. cleavage by LPL?
VLDL
5:1
ApoB100
ApoC-II
Which lipoprotein is considered "atherogenic"? What is its trig:cholesterol ratio? What apoprotein flags it for pick-up by the liver?
LDL
<10% trigs:50-60% cholesterol
ApoB100
Which apoprotein flags a lipoprotein for cleavage by LPL?