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unintended response to a drug, also called side effect
adverse effects
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the ability of a generic drug to reach blood levles equivalent to those reached by a brand name drug
biologic equivalence
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a chemical substance used in diagnosis, treatment, or prevention of disease
drug
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the use of experience of statistical probabilities for making drug choices
empirical
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the official name of a drug listend in a pharmacopeia
generic name
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the intended use for a drug, usually the use approved by the food and drug administration
indication
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a drug secured by a prescription
legnd drug
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the study of drugs and their effects on living tissue
pharmacology
-
the changes wihthin a body caused by a drug
pharmacologic effects
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a published source of drug information based on drugs in a given geographical area
pharmacopeia
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the brand name of a drug
proprietary name
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ADE
adverse drug effect or adverse side effect
-
FDA
food and drug administration
-
HCP
health care professional
-
OTC
over the counter drug
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what is the role of pharm in the DH process of care? (this is a long one might as well just cheat)
- drugs used entered into TX record including drug, dose and ROA
- Recommended drugs to pt or samples given recorded in TX record with pt instructions
- drug and herbal supplements from HHX review investigated for drug effects for TX modifications
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what are some online sources for drug references? 4
- hippocates web site
- PDR web site
- MedlinePlus
- Governmental drug information site
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what agency regulates the safety and effectiveness of drugs?
FDA
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what agency enforces the Modernization Act?
FDA
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what does the Modernization Act regulate?
labeling and packaging of drug products
-
what agency administers the requirements of the controlled substances act?
DEA
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what Act is used to prevent drug abuse and dependence, including treatment and rehabilitation for drug dependancy. Also includes regulations for manufacturing distribution and dispensing of controlled substances
comprehensive drug abuse prevention and control act of 1970
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what act determines schedules of drugs
comprehensive drug abuse prevention and control act of 1970
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what are the three names a drug goes thru during trials?
- chemical name
- generic name
- proprietary name
-
what is the official name of a drug derived from the chemical name called?
generic name
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what is the brand or trade name such as tylenol called?
proprietary name
-
what is a drug called that can only be secrued with a prescription?
legend drug
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what are the two types of ROAs
-
what is the safest most common and convenient ROA
enteral
-
what are the five types of parenteral ROAs
intravenous, subcutaneous, intramusclar, inhalation and topical
-
what route is most predictaable and used in emergency situations
IV route
-
what route is the least safe and the most likely to cause allergic drug reactions?
topical
-
what ROA is the most unpredicatable?
enteral
-
the force of attraction of a molecule to a receptor site
affinity
-
a drug that has a direct stimulatroy effect on a receptor
agonist
-
a drug that interferes with the action of an agonist
antagonist
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the dose above which no further beneficial drug effect will occur
ceiling dose
-
the admistraion of a drug through the gastrointestinal tract by mouth
enteral
-
the magnitude of response obtained from optimal receptr site occupancy by a drug
effficacy
-
the time it takes for half the drug to be removed from the body
half life
-
the ability to cause an effect or action
intrinsic activity
-
the administration of a drug bypassing the GI tract usually through injection into the body in various ways but also including inhalation and toical administration
parenteral
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a drug with affinity for the receptor site but unable to produce a stron effect or action
partial agonist
-
the mechanisms of drug action involving biochemical and physiologic effects of drugs
pharmacodynamics
-
the absorption distribution metabolism and excretion of a drug
pharmacokinetics
-
the use of pharmacologic agents to diagnose treat or prevent disease
pharmacotherapeutics
-
the concentration at which the drug elicits 50% of its maximal response realted to the drugs affinity for teh receptor
potency
-
a specialized area on a cell or within a cell wher a drug acts to initiate a series of biochemical and physiologic effects
receptor site
-
drug that produces a significant physiologic response when only a relatively small number of receptors are occupied
strong agonists
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overdose, undesirable effects or poisoning
toxicity
-
-
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ROA
route of administration
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