What happens when you have a great deal of atelectasis?
↑ PaCO2 (hpercapnia) not able to ventilate
Which cause acidosis
↓ PaO2 (hypoxemia)
How does gas exchange, if you are ventilating a pt. less than dead space volumes?
HFOV (High Frequency Oscillation Ventilation)
What are the typical blood gases you will see in a pt. w/ BPD?
Chronic lung disease (COPD)
pH normal (compensated)
↑ CO2
↓ O2
↑ Bicarb
If need to intubate a neonate/infant w/ RDS, what do you do?
Mechanical ventilation ( the low Vt strategy)
Use the lowest PIP (peak inspiratory pressures)
Use the lowest FiO2 to maintain blood gases
What is the primary disease of prematurity?
rds
What do you think will happen to the lungs if all this air escaping into the interstitium? (Interstitium surrounds and supports the lungs?
The air will compress the lungs
Compress the vessels
Cause ↓ lung compliance
What happens to the ventilator settings if you have lung compliance?
Will need to use higher ventilator settings
What is the major underling cause of RDS?
surfactant deficiency
What are some complications associated w/ RDS?
ICH
Barotrauma
NEC
PIE
ROP
How is RDS treated?
If need assistance w/ RR use CPAP noninvasive b/c you want to minimize barotrauma
Use lower Vt strategy, which will minimize barotrauma
HFOV
Thermoregulation
Surfactant replacement therapy (SRT)
which ↓ surfactant
What is BPD?
Bronchopulmonary Dysplasia
It is a result from the adverse effects of mechanical ventilation
What are the adverse effects of mechanical ventilation?
Extensive lung injury by barotrauma (which is too much pressure)
Volume trauma ( trauma from excessive volumes)
How do you treat BPD?
Oscillator
Prevention/treatment is low Vt strategy
Minimize barotrauma
Permissive Hypercapnia
Surfactant Replacement Therapy (SRT)
ECMO
Having sever oxygenation issues
Nitric Oxide
Vitamin A
Hydration
Close off PDA # 1
What is ROP?
Retinopathy of Prematurity
It is the constriction of the blood vessels
too much oxygen causing the retina blood vessels to constrict and the blood vessels die and forms a scar in the lens of the eyes and this is how the blindness occurs.
How can you prevent ROP?
Use very cautious use of oxygen
The more premature they are the higher the incidence of ROP.
Need to set Spo2 high alarm
Which neonates are at the greatest risk for developing ICH/IVH?
Less than 32 weeks gestation and less than 1500 grams
What is the most common cause of ICH/IVH?
Premature of the CNS
Meaning the head
What is PIE?
Pulmonary Interstitial Emphysema
This is a leak syndrome
Where the air escapes into the pulmonary interstitium
How do you treat PIE?
HFOV or low Vt strategy
B/c increase pressure will worsen it. This is what caused PIE in the 1st place.
What are two complications associated w/ O2 administration?
Knock out respiratory drive
Nitrogen washout - Leading to absorption atelectasis
ROP
What is a quick method used to diagnose pneumothorax in neonate and young infants?
Transillumination
What do you set in pressure control ventilation?
Pressure (PIP)
Influence of airway resistance, lung compliance
Rate
I-time- Vt varies
On the Avea what modes is available only in the neonatal size that is pressure based?
TCLP
Timed Cycle pressure Limited
you set a pressure (neonate/infants)
When setting a PIP on a vent. For a neonate/infant, what do you look for?
Ehxhaled Vt
Good chest rise and fall
Good chest expansion
Look at X-Ray- Will count the number of ribs to which that lung is inflated (rib 8-9).
if not inflated enough will turn up the PIP
If lungs are over inflated they will turn down the PIP